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Related Party Transactions - Additional Information (Details)
1 Months Ended 3 Months Ended 6 Months Ended 9 Months Ended
Oct. 31, 2021
USD ($)
ft²
Sep. 30, 2022
USD ($)
shares
Sep. 30, 2021
USD ($)
Mar. 31, 2021
USD ($)
Sep. 30, 2022
USD ($)
Founder
shares
Sep. 30, 2021
USD ($)
Jun. 30, 2021
shares
Related Party Transaction [Line Items]              
Number of founder shareholders | Founder         3    
Sublease income   $ 331,000     $ 993,000    
Other income (expense)   10,431,000 $ (4,892,000)   (1,378,000) $ 21,960,000  
Office and Laboratory Space              
Related Party Transaction [Line Items]              
Operating lease term             12 years
Founder Shareholders | Scientific Consulting and Other Expenses              
Related Party Transaction [Line Items]              
Payments received from (made to) related parties   100,000 100,000   300,000 300,000  
Verve Therapeutics, Inc.              
Related Party Transaction [Line Items]              
Equity securities   18,800,000     18,800,000    
Other income (expense)   10,400,000 $ (4,900,000)   (1,400,000) 22,000,000.0  
Verve Therapeutics, Inc. | Office and Laboratory Space              
Related Party Transaction [Line Items]              
Sublease area of rented space | ft² 12,000            
Operating lease term 1 year            
Sublease, commencement month and year 2021-12            
Rental payment over term of sublease $ 1,400,000            
Sublease income   $ 300,000     $ 1,000,000.0    
Verve Therapeutics, Inc. | Common Stock              
Related Party Transaction [Line Items]              
Equity shares held | shares   546,970     546,970   546,970
Verve Therapeutics, Inc. | Research and Development Expense              
Related Party Transaction [Line Items]              
Purchases from related party   $ 400,000     $ 400,000 $ 200,000  
Reimbursed Costs | Prime Agreement | Interest and Other Income (Expense), Net | Prime Medicine Inc | Monthly Fee              
Related Party Transaction [Line Items]              
Income from related party       $ 30,000.0      
Orbital              
Related Party Transaction [Line Items]              
Percentage of fully diluted equity interest   31.50%     31.50%