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Segment Data - Schedule of Reportable Segment Net Revenues and Loss (Details) - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2024 | Dec. 31, 2023 | Dec. 31, 2022
Segment Reporting Information [Line Items] |  |  |
License and collaboration revenue | $ 63,518 | $ 377,709 | $ 60,920
Research and development expense | 367,561 | 437,381 | 311,594
General and administrative expenses | 111,525 | 116,813 | 87,805
Facility and information technology related expenses | 55,911 | 53,804 | 41,448
Depreciation and amortization | 21,925 | 20,012 | 14,147
Stock-based compensation | 120,662 | 98,647 | 84,321
Interest and other income | 49,094 | 46,676 | 15,297
Income tax expense | 39 | 1,366 | 3,410
Other segment items | (16,895) | (46,821) | 33,938
Net loss | (376,742) | (132,527) | (289,088)
External Research And Development Expenses [Member] |  |  |
Segment Reporting Information [Line Items] |  |  |
Research and development expense | 115,189 | 155,063 | 112,380
External General And Administrative Expenses [Member] |  |  |
Segment Reporting Information [Line Items] |  |  |
General and administrative expenses | 25,115 | 40,016 | 25,885
Employee Related Expenses [Member] |  |  |
Segment Reporting Information [Line Items] |  |  |
Research and development expense | 98,796 | 109,878 | 89,547
General and administrative expenses | $ 34,822 | $ 31,305 | $ 28,105

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