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Consolidated Statements of Operations and Other Comprehensive Loss - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Income Statement [Abstract]      
License and collaboration revenue $ 63,518 $ 377,709 $ 60,920
Revenue, Product and Service [Extensible List] us-gaap:LicenseMember us-gaap:LicenseMember us-gaap:LicenseMember
Operating expenses:      
Research and development $ 367,561 $ 437,381 $ 311,594
General and administrative 111,525 116,813 87,805
Total operating expenses 479,086 554,194 399,399
Loss from operations (415,568) (176,485) (338,479)
Other income (expense):      
Change in fair value of derivative liabilities 2,272 7,500 23,900
Change in fair value of non-controlling equity investments (14,093) (18,592) 20,200
Change in fair value of contingent consideration liabilities 1,592 9,740 18,904
Interest and other income (expense), net 49,094 46,676 15,297
Total other income (expense) 38,865 45,324 78,301
Net loss before income taxes (376,703) (131,161) (260,178)
Provision for income taxes (39) (1,366) (3,410)
Loss from equity method investment     (25,500)
Net loss (376,742) (132,527) (289,088)
Unrealized gain (loss) on marketable securities 75 3,034 (2,380)
Comprehensive loss $ (376,667) $ (129,493) $ (291,468)
Net loss per common share, basic $ (4.58) $ (1.72) $ (4.13)
Net loss per common share, diluted $ (4.58) $ (1.72) $ (4.13)
Weighted - average common shares outstanding, basic 82,313,008 77,151,771 70,015,305
Weighted - average common shares outstanding, diluted 82,313,008 77,151,771 70,015,305