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Segment Data - Schedule of Reportable Segment Net Revenues and Loss (Details) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Segment Reporting Information [Line Items]      
License and collaboration revenue $ 63,518 $ 377,709 $ 60,920
Research and development expense 367,561 437,381 311,594
General and administrative expenses 111,525 116,813 87,805
Facility and information technology related expenses 55,911 53,804 41,448
Depreciation and amortization 21,925 20,012 14,147
Stock-based compensation 120,662 98,647 84,321
Interest and other income 49,094 46,676 15,297
Income tax expense 39 1,366 3,410
Other segment items (16,895) (46,821) 33,938
Net loss (376,742) (132,527) (289,088)
External Research And Development Expenses [Member]      
Segment Reporting Information [Line Items]      
Research and development expense 115,189 155,063 112,380
External General And Administrative Expenses [Member]      
Segment Reporting Information [Line Items]      
General and administrative expenses 25,115 40,016 25,885
Employee Related Expenses [Member]      
Segment Reporting Information [Line Items]      
Research and development expense 98,796 109,878 89,547
General and administrative expenses $ 34,822 $ 31,305 $ 28,105