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Fair Value of Financial Instruments - Schedule of Calculation of Estimated Fair Value of Success Payment Liabilities (Details) - Success Payment Liabilities
 3 Months Ended 12 Months Ended
Mar. 31, 2025
Dec. 31, 2024
Fair Value of Common Stock | Harvard    
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]    
Success payment liability measurement input 19.53 24.8
Fair Value of Common Stock | Broad Institute    
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]    
Success payment liability measurement input 19.53 24.8
Expected Volatility | Harvard    
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]    
Success payment liability measurement input 0.76 0.78
Expected Volatility | Broad Institute    
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]    
Success payment liability measurement input 0.79 0.81
Expected Term (years) | Minimum | Harvard    
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]    
Success payment liability, term 10 days 10 days
Expected Term (years) | Minimum | Broad Institute    
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]    
Success payment liability, term 10 days 10 days
Expected Term (years) | Maximum | Harvard    
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]    
Success payment liability, term 4 years 2 months 26 days 4 years 5 months 26 days
Expected Term (years) | Maximum | Broad Institute    
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]    
Success payment liability, term 5 years 1 month 9 days 5 years 4 months 9 days