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Condensed Consolidated Statements of Stockholders' Equity (Unaudited) - USD ($)
$ in Thousands
Total
Common Stock
Additional Paid-in Capital
Accumulated Other Comprehensive Income (Loss)
Accumulated Deficit
Beginning Balance at Dec. 31, 2023 $ 981,329 $ 816 $ 2,169,798 $ 604 $ (1,189,889)
Beginning Balance, Shares at Dec. 31, 2023   81,632,496      
Purchase of common stock under ESPP 1,398 $ 1 1,397    
Purchase of common stock under ESPP, Shares   76,461      
Vesting of restricted common stock   $ 4 (4)    
Vesting of restricted common stock, Shares   420,579      
Stock-based compensation 29,281   29,281    
Exercise of common stock options 1,676 $ 2 1,674    
Exercise of common stock options, Shares   151,291      
Other comprehensive income (loss) (1,525)     (1,525)  
Net loss (98,669)       (98,669)
Ending Balance at Mar. 31, 2024 913,490 $ 823 2,202,146 (921) (1,288,558)
Ending Balance, Shares at Mar. 31, 2024   82,280,827      
Beginning Balance at Dec. 31, 2024 733,545 $ 836 2,298,661 679 (1,566,631)
Beginning Balance, Shares at Dec. 31, 2024   83,633,069      
Purchase of common stock under ESPP 1,501 $ 1 1,500    
Purchase of common stock under ESPP, Shares   90,436      
Issuance of common stock and pre-funded warrants, net of issuance costs 470,478 $ 162 470,316    
Issuance of common stock and pre-funded warrants, net of issuance costs, Shares   16,151,686      
Vesting of restricted common stock   $ 6 (6)    
Vesting of restricted common stock, Shares   607,196      
Stock-based compensation 26,682   26,682    
Exercise of common stock options $ 719 $ 1 718    
Exercise of common stock options, Shares 74,707 74,707      
Other comprehensive income (loss) $ (519)     (519)  
Net loss (109,270)       (109,270)
Ending Balance at Mar. 31, 2025 $ 1,123,136 $ 1,006 $ 2,797,871 $ 160 $ (1,675,901)
Ending Balance, Shares at Mar. 31, 2025   100,557,094