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Segment Data - Schedule of Reportable Segment Net Revenues and Loss (Details) - USD ($)
 3 Months Ended
Mar. 31, 2025
Mar. 31, 2024
Segment Reporting Information [Line Items]    
License and collaboration revenue $ 7,470,000 $ 7,410,000
Research and development expense 98,816,000 84,818,000
General and administrative expenses 27,940,000 26,724,000
Facility and information technology related expenses 14,383,000 13,667,000
Depreciation and amortization 5,528,000 5,431,000
Stock-based compensation 26,682,000 29,281,000
Interest and other income (9,864,000) (11,849,000)
Income tax expense 0 0
Other segment items 534,000 5,961,000
Net loss (109,270,000) (98,669,000)
External Research And Development Expenses [Member]    
Segment Reporting Information [Line Items]    
Research and development expense 34,421,000 25,361,000
External General And Administrative Expenses [Member]    
Segment Reporting Information [Line Items]    
General and administrative expenses 5,373,000 5,066,000
Employee Related Expenses [Member]    
Segment Reporting Information [Line Items]    
Research and development expense 29,242,000 24,570,000
General and administrative expenses $ 10,441,000 $ 8,591,000