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v3.25.2

Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands | 6 Months Ended
--- | ---
Jun. 30, 2025 | Jun. 30, 2024
Operating activities |  |
Net loss | $ (211,561) | $ (189,720)
Adjustments to reconcile net loss to net cash provided by (used in) operating activities: |  |
Depreciation and amortization | 11,066 | 11,007
Amortization of investment discount (premiums) | (8,467) | (12,502)
Stock-based compensation expense | 51,049 | 60,885
Change in operating lease right-of-use assets | 5,297 | 4,755
Change in fair value of derivative liabilities | (3,407) | (2,600)
Change in fair value of contingent consideration liabilities | 55 | (1,646)
Change in fair value of non-controlling equity investments | (2,334) | 10,939
Changes in operating assets and liabilities: |  |
Prepaid expenses and other current assets | 2,827 | 714
Accounts payable | 6,435 | 3,057
Accrued expenses and other liabilities | (8,590) | (43,761)
Operating lease liabilities | (6,622) | (6,241)
Deferred revenue | (15,936) | (18,182)
Other long-term liabilities | (146) | 539
Net cash provided by (used in) operating activities | (180,334) | (182,756)
Investing activities |  |
Purchases of property and equipment | (6,201) | (4,399)
Purchases of marketable securities | (673,111) | (329,714)
Maturities of marketable securities | 383,812 | 368,142
Net cash provided by (used in) investing activities | (295,500) | 34,029
Financing activities |  |
Proceeds from issuance of common shares and pre-funded warrants, net of issuance costs | 470,513 | 0
Proceeds from issuances of stock under ESPP | 1,501 | 1,398
Repayment of equipment financings | 0 | (284)
Proceeds from exercise of stock options | 2,474 | 1,916
Net cash provided by (used in) financing activities | 474,488 | 3,030
Net change in cash, cash equivalents and restricted cash | (1,346) | (145,697)
Cash, cash equivalents and restricted cash—beginning of period | 290,111 | 444,614
Cash, cash equivalents and restricted cash—end of period | 288,765 | 298,917
Supplemental disclosure of cash flow information: |  |
Cash paid for interest | 0 | 22
Supplemental disclosure of non-cash investing and financing activities: |  |
Property and equipment additions in accounts payable and accrued expenses | 972 | 521
Operating lease liabilities arising from obtaining right-of-use assets | $ 0 | $ (1,273)

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