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Nature of the Business and Basis of Presentation - Additional Information (Details) - USD ($) | 1 Months Ended | 3 Months Ended | 6 Months Ended | 51 Months Ended |
--- | --- | --- | --- | --- | ---
Mar. 31, 2025 | Jun. 30, 2025 | Jun. 30, 2025 | Jun. 30, 2024 | Jun. 30, 2025 | Dec. 31, 2024
Nature Of Business And Basis Of Presentation [Line Items] |  |  |  |  |  |
Aggregate net proceeds from offering |  |  | $ 470,513,000 | $ 0 |  |
Accumulated deficit |  | $ 1,778,192,000 | 1,778,192,000 |  | $ 1,778,192,000 | $ 1,566,631,000
Cash, cash equivalents, and marketable securities |  | $ 1,200,000,000 | $ 1,200,000,000 |  | $ 1,200,000,000 |
Underwritten Public Offering |  |  |  |  |  |
Nature Of Business And Basis Of Presentation [Line Items] |  |  |  |  |  |
Stock sold during period shares, new issues | 16,151,686 |  |  |  |  |
Price per share of shares issued | $ 28.48 |  |  |  |  |
Aggregate net proceeds from offering | $ 470,500,000 |  |  |  |  |
Legal, accounting and other fees | $ 800,000 |  |  |  |  |
Pre-Funded Warrants |  |  |  |  |  |
Nature Of Business And Basis Of Presentation [Line Items] |  |  |  |  |  |
Warrants to purchase common stock | 1,404,988 |  |  |  |  |
Purchase price per warrant | $ 28.47 |  |  |  |  |
Jeffries LLC Sales Agreement |  |  |  |  |  |
Nature Of Business And Basis Of Presentation [Line Items] |  |  |  |  |  |
Stock sold during period shares, new issues |  | 0 | 0 |  | 13,769,001 |
Gross proceeds from issuance of common stock |  |  |  |  | $ 864,000,000 |
Jeffries LLC Sales Agreement | Common Stock |  |  |  |  |  |
Nature Of Business And Basis Of Presentation [Line Items] |  |  |  |  |  |
Stock sold during period shares, new issues |  |  |  |  | 13,769,001 |
Price per share of shares issued |  | $ 62.75 | $ 62.75 |  | $ 62.75 |
Jeffries LLC Sales Agreement | Maximum | ATM Offering |  |  |  |  |  |
Nature Of Business And Basis Of Presentation [Line Items] |  |  |  |  |  |
Commission rate |  |  |  |  | 3.00% |
Aggregate gross proceeds of shares authorized under ATM sales agreement |  | $ 1,100,000,000 | $ 1,100,000,000 |  | $ 1,100,000,000 |

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