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Condensed Consolidated Statements of Operations and Other Comprehensive Loss (Unaudited) - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2025
Sep. 30, 2024
Sep. 30, 2025
Sep. 30, 2024
Income Statement [Abstract]        
License and collaboration revenue $ 9,698,000 $ 14,269,000 $ 25,634,000 $ 33,451,000
Revenue, Product and Service [Extensible List] us-gaap:LicenseMember us-gaap:LicenseMember us-gaap:LicenseMember us-gaap:LicenseMember
Operating expenses:        
Research and development $ 109,769,000 $ 94,258,000 $ 310,343,000 $ 266,117,000
General and administrative 26,740,000 26,515,000 81,539,000 82,865,000
Total operating expenses 136,509,000 120,773,000 391,882,000 348,982,000
Loss from operations (126,811,000) (106,504,000) (366,248,000) (315,531,000)
Other income (expense):        
Change in fair value of derivative liabilities (2,757,000) (200,000) 650,000 2,400,000
Change in fair value of non-controlling equity investments 4,937,000 (2,064,000) 7,271,000 (13,003,000)
Change in fair value of contingent consideration liabilities 1,000,000 (27,000) 945,000 1,619,000
Interest and other income (expense), net 10,903,000 12,127,000 33,093,000 38,166,000
Total other income (expense) 14,083,000 9,836,000 41,959,000 29,182,000
Net loss before income taxes (112,728,000) (96,668,000) (324,289,000) (286,349,000)
Provision for income taxes     0 (39,000)
Net loss (112,728,000) (96,668,000) (324,289,000) (286,388,000)
Unrealized gain (loss) on marketable securities 780,000 2,869,000 111,000 1,155,000
Comprehensive loss $ (111,948,000) $ (93,799,000) $ (324,178,000) $ (285,233,000)
Net loss per common share, basic $ (1.1) $ (1.17) $ (3.32) $ (3.49)
Net loss per common share, diluted $ (1.1) $ (1.17) $ (3.32) $ (3.49)
Weighted - average common shares outstanding, basic 102,570,801 82,410,095 97,567,229 82,141,383
Weighted - average common shares outstanding, diluted 102,570,801 82,410,095 97,567,229 82,141,383