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Condensed Statements of Cash Flows (unaudited) - USD ($)
$ in Thousands
 9 Months Ended
Sep. 30, 2015
Sep. 30, 2014
Operating activities:    
Net loss $ (22,325) $ (7,245)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 289 89
Stock-based compensation 2,245 57
Non-cash interest expense   66
Amortization of discount or premium on short-term investments (14)  
Change in fair value of convertible notes payable   183
Amortization of debt issue costs 17 23
Deferred rent 54 38
Purchase of in-process research and development   1,607
Changes in assets and liabilities:    
Prepaid expenses and other current assets (723) (192)
Accounts payable and accrued liabilities 538 647
Accrued compensation 698 251
Other assets   (62)
Net cash used in operating activities (19,221) (4,538)
Investing activities:    
Purchases of short-term investments (49,938)  
Purchases of property and equipment (708) (845)
Net cash used in investing activities (50,646) (845)
Financing activities:    
Proceeds from initial public offering, net of offering costs 69,505  
Deferred initial public offering costs   (40)
Proceeds from exercise of stock options 116 10
Proceeds from issuance of convertible notes payable, net of offering costs   930
Net cash provided by financing activities 111,542 30,766
Net increase in cash and cash equivalents 41,675 25,383
Cash and cash equivalents at beginning of period 22,796 185
Cash and cash equivalents at end of period 64,471 25,568
Non-cash investing activity:    
Property and equipment acquired but not yet paid 269  
Non-cash financing activities:    
Deferred initial public offering costs paid in 2014 233  
Vesting of early exercised stock options 399  
Series A Convertible Preferred Stock    
Financing activities:    
Proceeds from issuance convertible preferred stock, net of offering costs   29,866
Non-cash financing activities:    
Conversion convertible preferred stock to common upon initial public offering 32,548  
Conversion of convertible notes payable and accrued interest to Series A convertible preferred shares   $ 2,682
Series B Convertible Preferred Stock    
Financing activities:    
Proceeds from issuance convertible preferred stock, net of offering costs 41,921  
Non-cash financing activities:    
Conversion convertible preferred stock to common upon initial public offering $ 41,921