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EQUITY INCENTIVE PLANS
 6 Months Ended
Jun. 30, 2025
Share-Based Payment Arrangement [Abstract]  
EQUITY INCENTIVE PLANS EQUITY INCENTIVE PLANS
2024 Equity Incentive Plan, 2020 Inducement Incentive Plan and 2015 Equity Incentive Plan
In May 2024, the Company’s board of directors approved and adopted and in July 2024, the Company’s stockholders approved the Company’s 2024 Equity Incentive Plan, which was amended in June 2025, or 2024 EIP. The 2024 EIP is the successor to and continuation of the Company’s 2015 Equity Incentive Plan, or 2015 EIP, previously approved and adopted in March 2015 by the Company’s board of directors and stockholders. The 2024 EIP became effective on July 18, 2024. Upon the effectiveness of the 2024 EIP, no additional awards were or will be granted under the 2015 EIP, although all outstanding stock awards granted under the 2015 EIP continue to be governed by the terms of the 2015 EIP. Under the 2024 EIP, the Company may grant stock options, stock appreciation rights, restricted stock, RSUs, and other awards to individuals who are employees, officers, directors or consultants of the Company.
In December 2020, the Company’s board of directors approved and adopted the 2020 Inducement Incentive Plan, which was most recently amended in February 2025, or 2020 IIP. Under the 2020 IIP, the Company may grant stock options, stock appreciation rights, restricted stock, RSUs, and other awards to individuals who were not previously employees or directors of the Company, or who are returning to employment following a bona fide period of non-employment with the Company, as an inducement material to such persons entering into employment with the Company.
Terms of stock award agreements, including vesting requirements, are determined by the board of directors (or the compensation and human capital committee thereof), subject to the provisions of the 2024 EIP, 2020 IIP and 2015 EIP. Stock options granted by the Company generally vest over a three- or four-year period. Certain stock options are subject to acceleration of vesting in the event of certain change of control transactions. The stock options may be granted for a term of up to 10 years from the date of grant. The exercise price for stock options granted under the 2024 EIP, 2020 IIP and 2015 EIP must be at a price no less than 100% of the fair value of the shares on the date of grant, provided that for an incentive stock option granted to an employee who at the time of grant owns stock representing more than 10% of the voting power of all classes of stock of the Company, the exercise price shall be no less than 110% of the value on the date of grant.
2015 Employee Stock Purchase Plan
In March 2015, the Company’s board of directors and stockholders approved and adopted the ESPP.
The ESPP allows substantially all employees to purchase the Company’s common stock through a payroll deduction at a price equal to 85% of the lower of the fair market value of the stock as of the beginning or the end of each purchase period. An employee’s payroll deductions under the ESPP are limited to 15% of the employee’s eligible compensation.
During the six months ended June 30, 2025 and 2024, 3,242 shares and 7,050 shares, respectively, were issued pursuant to the ESPP. As of June 30, 2025, total unrecognized compensation expense related to the ESPP was $0.1 million and is expected to be recognized over approximately 0.6 years.
Restricted Stock Units
The following table summarizes RSU activity during the six months ended June 30, 2025:
Number of
RSUs		Weighted Average Grant Date Fair Value
Outstanding at December 31, 2024177,273 $14.06 
RSUs granted275,410 21.26 
RSUs vested(34,876)17.14 
RSUs canceled(21,972)16.92 
Outstanding at June 30, 2025395,835 $18.64 
The weighted-average grant date fair value of RSUs granted by the Company during the six months ended June 30, 2024 was $13.60 per share. The total fair value of RSUs vested during the six months ended June 30, 2025 and 2024 was approximately $0.6 million and $0.7 million, respectively.
At June 30, 2025, estimated unrecognized compensation expense related to RSUs granted was approximately $6.5 million. This unrecognized compensation cost is expected to be recognized over a weighted-average period of approximately 2.8 years.
Stock Options
The following table summarizes stock option activity during the six months ended June 30, 2025:
Number of
Shares		Weighted
Average
Exercise Price		Weighted
Average
Remaining
Contractual Life in Years		Total Aggregate
Intrinsic Value (in thousands)
Outstanding at December 31, 20242,303,738 $18.50 8.84$29,729 
Options granted854,294 21.78 
Options exercised(82,648)15.86 
Options canceled(298,009)24.80 
Outstanding at June 30, 20252,777,375 $18.91 8.89$86,620 
Vested and expected to vest at June 30, 20252,777,375 $18.91 8.89$86,620 
Exercisable at June 30, 2025766,629 $26.80 7.53$20,649 
The intrinsic value of a stock option is the difference between the market price of the common stock at the measurement date and the exercise price of the option.
The weighted-average grant date fair value of stock options granted by the Company during the six months ended June 30, 2025, and 2024 was $16.00 and $9.72 per share, respectively.
As of June 30, 2025, total unrecognized share-based compensation expense related to unvested stock options was approximately $22.8 million. This unrecognized compensation cost is expected to be recognized over a weighted-average period of approximately 2.4 years.
Stock-based compensation expense recognized for RSUs, stock options, and the ESPP has been reported in the condensed consolidated statements of operations and comprehensive loss as follows (in thousands):
Three Months Ended
June 30,		Six Months Ended
June 30,
2025202420252024
Stock-based compensation expense:
Research and development$848 $297 $1,298 $524 
General and administrative2,107 330 3,398 743 
Stock-based compensation expense recorded in continuing operations2,955 627 4,696 1,267 
Stock-based compensation expense recorded in discontinued operations— 76 — 231 
Total stock-based compensation expense$2,955 $703 $4,696 $1,498