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Condensed Consolidated Statements of Changes in Convertible Preferred Stock and Stockholders’ Equity (Deficit) (unaudited) - USD ($)
$ in Thousands
Total
Underwritten Public Offerings
At-The-Market Offering
Private Placement
Common Stock
Common Stock
Underwritten Public Offerings
Common Stock
At-The-Market Offering
Additional Paid-In Capital
Additional Paid-In Capital
Underwritten Public Offerings
Additional Paid-In Capital
At-The-Market Offering
Additional Paid-In Capital
Private Placement
Accumulated Deficit
Series A Convertible Voting Preferred Stock
Series A Convertible Voting Preferred Stock
Preferred Stock
Series A Convertible Voting Preferred Stock
Preferred Stock
Private Placement
Series X Convertible Preferred Stock
Series X Convertible Preferred Stock
Preferred Stock
Balance, beginning (in shares) at Dec. 31, 2023                           0     2,104,472
Balance, beginning at Dec. 31, 2023 $ (8,210)       $ 1     $ 433,220       $ (441,431)   $ 0     $ 0
Balance, beginning (in shares) at Dec. 31, 2023         4,530,113                        
Increase (Decrease) in Stockholders' Equity [Roll Forward]                                  
Issuance of common stock upon vesting of restricted stock units (in shares)         31,583                        
Value of shares withheld to fund payroll taxes (39)             (39)                  
Stock-based compensation 795             795                  
Net loss (10,326)                     (10,326)          
Balance, ending (in shares) at Mar. 31, 2024                           0     2,104,472
Balance, ending at Mar. 31, 2024 (17,780)       $ 1     433,976       (451,757)   $ 0     $ 0
Balance, ending (in shares) at Mar. 31, 2024         4,561,696                        
Balance, beginning (in shares) at Dec. 31, 2023                           0     2,104,472
Balance, beginning at Dec. 31, 2023 (8,210)       $ 1     433,220       (441,431)   $ 0     $ 0
Balance, beginning (in shares) at Dec. 31, 2023         4,530,113                        
Increase (Decrease) in Stockholders' Equity [Roll Forward]                                  
Issuance of common stock under Employee Stock Purchase Plan 55                                
Net loss (101,535)                                
Balance, ending (in shares) at Jun. 30, 2024                           240,000     2,104,472
Balance, ending at Jun. 30, 2024 130,936       $ 1     673,901       (542,966)   $ 0     $ 0
Balance, ending (in shares) at Jun. 30, 2024         4,568,991                        
Balance, beginning (in shares) at Mar. 31, 2024                           0     2,104,472
Balance, beginning at Mar. 31, 2024 (17,780)       $ 1     433,976       (451,757)   $ 0     $ 0
Balance, beginning (in shares) at Mar. 31, 2024         4,561,696                        
Increase (Decrease) in Stockholders' Equity [Roll Forward]                                  
Issuance of common stock upon conversion (in shares)                             240,000    
Issuance of stock, net of issuance costs       $ 239,167             $ 239,167            
Issuance of common stock upon vesting of restricted stock units (in shares)         245                        
Issuance of common stock under Employee Stock Purchase Plan (in shares)         7,050                        
Issuance of common stock under Employee Stock Purchase Plan 55             55                  
Stock-based compensation 703             703                  
Net loss (91,209)                     (91,209)          
Balance, ending (in shares) at Jun. 30, 2024                           240,000     2,104,472
Balance, ending at Jun. 30, 2024 130,936       $ 1     673,901       (542,966)   $ 0     $ 0
Balance, ending (in shares) at Jun. 30, 2024         4,568,991                        
Balance, beginning (in shares) at Dec. 31, 2024                         204,725 204,725   2,104,472 2,104,472
Balance, beginning at Dec. 31, 2024 $ 163,308       $ 1     774,565       (611,258)   $ 0     $ 0
Balance, beginning (in shares) at Dec. 31, 2024 10,946,635       10,946,635                        
Increase (Decrease) in Stockholders' Equity [Roll Forward]                                  
Issuance of common stock upon conversion of Series X Convertible Preferred Stock (in shares)         564,632                       (1,129,264)
Issuance of common stock upon exercise of pre-funded warrants (in shares)         657,052                        
Issuance of common stock upon exercise of options (in shares)         6,855                        
Issuance of common stock upon exercise of options $ 113             113                  
Issuance of common stock upon vesting of restricted stock units (in shares)         33,976                        
Stock-based compensation 1,741             1,741                  
Net loss (23,480)                     (23,480)          
Balance, ending (in shares) at Mar. 31, 2025                           204,725     975,208
Balance, ending at Mar. 31, 2025 141,682       $ 1     776,419       (634,738)   $ 0     $ 0
Balance, ending (in shares) at Mar. 31, 2025         12,209,150                        
Balance, beginning (in shares) at Dec. 31, 2024                         204,725 204,725   2,104,472 2,104,472
Balance, beginning at Dec. 31, 2024 $ 163,308       $ 1     774,565       (611,258)   $ 0     $ 0
Balance, beginning (in shares) at Dec. 31, 2024 10,946,635       10,946,635                        
Increase (Decrease) in Stockholders' Equity [Roll Forward]                                  
Issuance of common stock upon conversion of Series X Convertible Preferred Stock (in shares)                               1,129,264  
Issuance of common stock upon exercise of options (in shares) 82,648                                
Issuance of common stock under Employee Stock Purchase Plan $ 33                                
Net loss (49,198)                                
Balance, ending (in shares) at Jun. 30, 2025                         194,769 194,769   975,208 975,208
Balance, ending at Jun. 30, 2025 $ 501,173       $ 2     1,161,627       (660,456)   $ 0     $ 0
Balance, ending (in shares) at Jun. 30, 2025 23,234,839       23,234,839                        
Balance, beginning (in shares) at Mar. 31, 2025                           204,725     975,208
Balance, beginning at Mar. 31, 2025 $ 141,682       $ 1     776,419       (634,738)   $ 0     $ 0
Balance, beginning (in shares) at Mar. 31, 2025         12,209,150                        
Increase (Decrease) in Stockholders' Equity [Roll Forward]                                  
Issuance of common stock upon conversion (in shares)           9,147,727 177,121                    
Issuance of stock, net of issuance costs   $ 376,910 $ 4,121   $ 1       $ 376,909 $ 4,121              
Issuance of common stock upon conversion of Series X Convertible Preferred Stock (in shares)         696,920                 (9,956)      
Issuance of common stock upon exercise of pre-funded warrants (in shares)         924,312                        
Issuance of common stock upon exercise of options (in shares)         75,467                        
Issuance of common stock upon exercise of options 1,190             1,190                  
Issuance of common stock upon vesting of restricted stock units (in shares)         900                        
Issuance of common stock under Employee Stock Purchase Plan (in shares)         3,242                        
Issuance of common stock under Employee Stock Purchase Plan 33             33                  
Stock-based compensation 2,955             2,955                  
Net loss (25,718)                     (25,718)          
Balance, ending (in shares) at Jun. 30, 2025                         194,769 194,769   975,208 975,208
Balance, ending at Jun. 30, 2025 $ 501,173       $ 2     $ 1,161,627       $ (660,456)   $ 0     $ 0
Balance, ending (in shares) at Jun. 30, 2025 23,234,839       23,234,839