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Agreements - Additional Information (Detail) $ in Thousands							1 Months Ended		3 Months Ended	12 Months Ended				36 Months Ended
Agreements - Additional Information (Detail) $ in Thousands	Jul. 11, 2025 USD ($)	Jul. 11, 2024 USD ($)	Jul. 11, 2023 USD ($)	Jan. 24, 2023	Jul. 11, 2022 USD ($)	Oct. 26, 2012	Jul. 31, 2023 USD ($) shares	Jul. 31, 2023 SFr / shares	Dec. 31, 2023 USD ($)	Dec. 31, 2024 USD ($)	Dec. 31, 2024 USD ($) SFr / shares	Dec. 31, 2023 USD ($)	Dec. 31, 2022 USD ($)	Jul. 11, 2025 USD ($)	Oct. 26, 2023 USD ($)	Jul. 19, 2023
License Agreement [Line Items]
Research and development expenses										$ 12,648		$ 93,150	$ 19,789
Asset acquisition equity interests issued or issuable number of shares issued \| shares							1,414,688
Asset Acquisition Percentage Of Outstanding Ordinary Shares							11.26%
U.S. Rights for FYCOMPA [Member]
License Agreement [Line Items]
Date on which strategic collaboration is entered into				Jan. 24, 2023
Contingent consideration liability										25,000	$ 25,000
Payments to acquire productive assets										$ 164,200
U.S. Rights for FYCOMPA [Member] \| Royalty More Than Ten Million And Less Than Hundred Million [Member]
License Agreement [Line Items]
Percentage of royalty on net sales										6.00%
U.S. Rights for FYCOMPA [Member] \| Royalty More Than Ten Million And Less Than Hundred Million [Member] \| Royalty Agreement Terms [Member]
License Agreement [Line Items]
Percentage of royalty on net sales										12.00%
U.S. Rights for FYCOMPA [Member] \| Royalty More Than Hundred Million And Less Than Hundred And Twenty Five Million [Member]
License Agreement [Line Items]
Percentage of royalty on net sales										8.50%
U.S. Rights for FYCOMPA [Member] \| Royalty More Than Hundred Million And Less Than Hundred And Twenty Five Million [Member] \| Royalty Agreement Terms [Member]
License Agreement [Line Items]
Percentage of royalty on net sales										17.00%
U.S. Rights for FYCOMPA [Member] \| Royalty More Than Hundred And Twenty Five Million [Member]
License Agreement [Line Items]
Percentage of royalty on net sales										11.00%
Net sales royalty threshold										$ 125,000
U.S. Rights for FYCOMPA [Member] \| Royalty More Than Hundred And Twenty Five Million [Member] \| Royalty Agreement Terms [Member]
License Agreement [Line Items]
Percentage of royalty on net sales										22.00%
Vamorolone [Member]
License Agreement [Line Items]
Payments to acquire productive assets							$ 75,000
Asset acquisition equity interests issued or issuable number of shares issued \| shares							1,414,688
Asset Acquisition Percentage Of Outstanding Ordinary Shares							11.26%
Asset Acquisition Investment Share Price \| SFr / shares											$ 9.477
Closing Market Price \| SFr / shares								SFr 8.25
Foreign Currency Exchange Rate, Translation																1.1537
Collaborative arrangement, milestone payment obligation															$ 36,000
Payment on milestone payment									$ 36,000
Capitalized amortized Cost									$ 36,000
Finite-lived intangible asset, useful life									10 years 6 months			10 years 6 months
AGAMREE [Member] \| Royalty Less Than Hundred Million [Member]
License Agreement [Line Items]
Percentage of royalty on net sales										5.00%
AGAMREE [Member] \| Royalty More Than Hundred Million And Less Than Two Hundred Million [Member]
License Agreement [Line Items]
Percentage of royalty on net sales										7.00%
AGAMREE [Member] \| Royalty More Than Two Hundred Million And Less Than Three Hundred Million [Member]
License Agreement [Line Items]
Percentage of royalty on net sales										9.00%
AGAMREE [Member] \| Royalty More Than Three Hundred Million [Member]
License Agreement [Line Items]
Percentage of royalty on net sales										11.00%
AGAMREE [Member] \| Royalty Less Than Two Hundred Fifty Million [Member]
License Agreement [Line Items]
Percentage of royalty on net sales										7.00%
AGAMREE [Member] \| Royalty More Two Hundred And Fifty Million And Less Than Five Hundred Million [Member]
License Agreement [Line Items]
Percentage of royalty on net sales										8.50%
AGAMREE [Member] \| Royalty More Than Five Hundred Million And Less Than Seven Hundred Fifty Million [Member]
License Agreement [Line Items]
Percentage of royalty on net sales										10.00%
AGAMREE [Member] \| Royalty More Seven Hundred And Fifty Million And Less Than One Billion [Member]
License Agreement [Line Items]
Percentage of royalty on net sales										12.00%
AGAMREE [Member] \| Royalty More Than One Billion And Less Than Two Billion [Member]
License Agreement [Line Items]
Percentage of royalty on net sales										13.00%
AGAMREE [Member] \| Royalty More Than Two Billion [Member]
License Agreement [Line Items]
Percentage of royalty on net sales										15.00%
AGAMREE [Member] \| Royalty For Santhera Sales Based Milestones [Member]
License Agreement [Line Items]
Net sales based milestone to royalty threshold										$ 105,000
AGAMREE [Member] \| Royalty For Additional Indications And Milestones Of Up To Fifty Million More [Member]
License Agreement [Line Items]
Percentage of royalty payable to sales based milestone										11.00%
AGAMREE [Member] \| Royalty For Additional Indications And Milestones [Member]
License Agreement [Line Items]
Contingent consideration liability										$ 50,000	$ 50,000
Minimum [Member] \| U.S. Rights for FYCOMPA [Member] \| Royalty More Than Ten Million And Less Than Hundred Million [Member]
License Agreement [Line Items]
Net sales royalty threshold										10,000
Minimum [Member] \| U.S. Rights for FYCOMPA [Member] \| Royalty More Than Ten Million And Less Than Hundred Million [Member] \| Royalty Agreement Terms [Member]
License Agreement [Line Items]
Net sales royalty threshold										10,000
Minimum [Member] \| U.S. Rights for FYCOMPA [Member] \| Royalty More Than Hundred Million And Less Than Hundred And Twenty Five Million [Member]
License Agreement [Line Items]
Net sales royalty threshold										100,000
Minimum [Member] \| U.S. Rights for FYCOMPA [Member] \| Royalty More Than Hundred Million And Less Than Hundred And Twenty Five Million [Member] \| Royalty Agreement Terms [Member]
License Agreement [Line Items]
Net sales royalty threshold										100,000
Minimum [Member] \| U.S. Rights for FYCOMPA [Member] \| Royalty More Than Hundred And Twenty Five Million [Member] \| Royalty Agreement Terms [Member]
License Agreement [Line Items]
Net sales royalty threshold										125,000
Minimum [Member] \| AGAMREE [Member] \| Royalty More Than Hundred Million And Less Than Two Hundred Million [Member]
License Agreement [Line Items]
Net sales royalty threshold										100,000
Minimum [Member] \| AGAMREE [Member] \| Royalty More Than Two Hundred Million And Less Than Three Hundred Million [Member]
License Agreement [Line Items]
Net sales royalty threshold										200,000
Minimum [Member] \| AGAMREE [Member] \| Royalty More Than Three Hundred Million [Member]
License Agreement [Line Items]
Net sales royalty threshold										300,000
Minimum [Member] \| AGAMREE [Member] \| Royalty More Two Hundred And Fifty Million And Less Than Five Hundred Million [Member]
License Agreement [Line Items]
Net sales royalty threshold										250,000
Minimum [Member] \| AGAMREE [Member] \| Royalty More Than Five Hundred Million And Less Than Seven Hundred Fifty Million [Member]
License Agreement [Line Items]
Net sales royalty threshold										500,000
Minimum [Member] \| AGAMREE [Member] \| Royalty More Seven Hundred And Fifty Million And Less Than One Billion [Member]
License Agreement [Line Items]
Net sales royalty threshold										750,000
Minimum [Member] \| AGAMREE [Member] \| Royalty More Than One Billion And Less Than Two Billion [Member]
License Agreement [Line Items]
Net sales royalty threshold										1,000,000
Minimum [Member] \| AGAMREE [Member] \| Royalty More Than Two Billion [Member]
License Agreement [Line Items]
Net sales royalty threshold										2,000,000
Maximum [Member] \| U.S. Rights for FYCOMPA [Member] \| Royalty More Than Ten Million And Less Than Hundred Million [Member]
License Agreement [Line Items]
Net sales royalty threshold										100,000
Maximum [Member] \| U.S. Rights for FYCOMPA [Member] \| Royalty More Than Ten Million And Less Than Hundred Million [Member] \| Royalty Agreement Terms [Member]
License Agreement [Line Items]
Net sales royalty threshold										100,000
Maximum [Member] \| U.S. Rights for FYCOMPA [Member] \| Royalty More Than Hundred Million And Less Than Hundred And Twenty Five Million [Member]
License Agreement [Line Items]
Net sales royalty threshold										125,000
Maximum [Member] \| U.S. Rights for FYCOMPA [Member] \| Royalty More Than Hundred Million And Less Than Hundred And Twenty Five Million [Member] \| Royalty Agreement Terms [Member]
License Agreement [Line Items]
Net sales royalty threshold										125,000
Maximum [Member] \| AGAMREE [Member] \| Royalty Less Than Hundred Million [Member]
License Agreement [Line Items]
Net sales royalty threshold										100,000
Maximum [Member] \| AGAMREE [Member] \| Royalty More Than Hundred Million And Less Than Two Hundred Million [Member]
License Agreement [Line Items]
Net sales royalty threshold										200,000
Maximum [Member] \| AGAMREE [Member] \| Royalty More Than Two Hundred Million And Less Than Three Hundred Million [Member]
License Agreement [Line Items]
Net sales royalty threshold										300,000
Maximum [Member] \| AGAMREE [Member] \| Royalty Less Than Two Hundred Fifty Million [Member]
License Agreement [Line Items]
Net sales royalty threshold										250,000
Maximum [Member] \| AGAMREE [Member] \| Royalty More Two Hundred And Fifty Million And Less Than Five Hundred Million [Member]
License Agreement [Line Items]
Net sales royalty threshold										500,000
Maximum [Member] \| AGAMREE [Member] \| Royalty More Than Five Hundred Million And Less Than Seven Hundred Fifty Million [Member]
License Agreement [Line Items]
Net sales royalty threshold										750,000
Maximum [Member] \| AGAMREE [Member] \| Royalty More Seven Hundred And Fifty Million And Less Than One Billion [Member]
License Agreement [Line Items]
Net sales royalty threshold										1,000,000
Maximum [Member] \| AGAMREE [Member] \| Royalty More Than One Billion And Less Than Two Billion [Member]
License Agreement [Line Items]
Net sales royalty threshold										$ 2,000,000
License Agreement with BioMarin [Member]
License Agreement [Line Items]
Date on which strategic collaboration is entered into						Oct. 26, 2012
Percentage of royalty on net sales										3.50%
Net sales royalty threshold										$ 100,000
License Agreement with BioMarin [Member] \| Minimum [Member]
License Agreement [Line Items]
Royalty agreement period										7 years
Percentage of royalty on net sales										7.00%
License Agreement with BioMarin [Member] \| Maximum [Member]
License Agreement [Line Items]
Percentage of royalty on net sales										10.00%
License Agreement For RUZURGI [Member]
License Agreement [Line Items]
Date on which strategic collaboration is entered into					Jul. 11, 2022
Minimum royalty	$ 3,000	$ 3,000	$ 3,000		$ 3,000									$ 3,000
Amount of minimum royalty payable maturity terms not met										$ 5,000
Research and development expenses					4,100
Up front payment					$ 10,000
Asset acquisition purchase price consideration		$ 10,000	$ 10,000
License Agreement For RUZURGI [Member] \| Minimum [Member]
License Agreement [Line Items]
Percentage of minimum royalty payable to net sales										1.25%
License Agreement For RUZURGI [Member] \| Maximum [Member]
License Agreement [Line Items]
Percentage of minimum royalty payable to net sales										2.50%