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OTHER EXPENSE (INCOME), NET | 12 Months Ended
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Dec. 31, 2020
Other Income and Expenses [Abstract] |
OTHER EXPENSE (INCOME), NET | OTHER EXPENSE (INCOME), NET Other expense (income), net for the years 2020, 2019 and 2018 consists of:
(in millions) |  | 2020 |  | 2019 |  | 2018
Litigation and other matters |  | $ | 422 |  |  | $ | 1,401 |  |  | $ | (27) |
Acquired in-process research and development costs |  | 32 |  |  | 41 |  |  | 1 |
Net (gain) loss on sales of assets |  | (1) |  |  | (31) |  |  | 6 |
Acquisition-related costs |  | — |  |  | 8 |  |  | 1 |
Other, net |  | 1 |  |  | (5) |  |  | (1) |
Other expense (income), net |  | $ | 454 |  |  | $ | 1,414 |  |  | $ | (20) |
In 2020, Litigation and other matters of $422 million includes net charges related to the U.S. Securities Litigation, the SEC Investigation and the Canadian Securities Litigation and related opt-outs. In 2020, Litigation and other matters also includes an insurance recovery related to a certain litigation matter. In 2019, Litigation and other matters of $1,401 million includes the settlement of a legacy U.S. securities class action matter (which is subject to an objector’s appeal of the final court approval). In 2018, Litigation and other matters of $27 million includes a favorable adjustment of $40 million related to the Salix legacy litigation matter. These matters and other significant matters are discussed in further detail in Note 20, "LEGAL PROCEEDINGS". In 2020 and 2019, Acquired in-process research and development costs of $32 million and $41 million, primarily consist of costs associated with the upfront payments to enter into certain exclusive licensing agreements. In 2019, Net (gain) loss on sales of assets includes $20 million related to the achievement of a milestone related to a certain product.

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- Definition The entire disclosure for other income or other expense items (both operating and nonoperating). Sources of nonoperating income or nonoperating expense that may be disclosed, include amounts earned from dividends, interest on securities, profits (losses) on securities, net and miscellaneous other income or income deductions. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 720 -URI http://asc.fasb.org/topic&trid=2122503 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 610 -URI http://asc.fasb.org/topic&trid=49130413 + Details
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