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Operating Leases - Additional Information (Details) - USD ($) $ in Thousands | 12 Months Ended
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Dec. 31, 2021 | Dec. 31, 2020 | Dec. 31, 2019
Operating Leased Assets [Line Items] |  |  |
Right-of-use assets | $ 3,898 | $ 5,205 |
Operating lease liability | 5,181 |  |
Operating lease cost | 1,700 | 1,500 | $ 1,500
Cash paid included in operating lease liabilities included in cash flow from operating activities | $ 1,900 | $ 1,700 | $ 1,700
South San Francisco, California |  |  |
Operating Leased Assets [Line Items] |  |  |
Operating lease, remaining lease term | 2 years 7 months 6 days |  |
Operating lease, discount rate | 7.00% |  |
Operating lease option to extend | true |  |
Operating lease renewal term | 2 years |  |
South San Francisco, California | Second Amendment |  |  |
Operating Leased Assets [Line Items] |  |  |
Operating lease, discount rate | 6.00% |  |
South San Francisco, California | Lease Agreement | Laboratory and Office Facilities |  |  |
Operating Leased Assets [Line Items] |  |  |
Lease expiration date | Jul. 31, 2024 |  |
South San Francisco | Laboratory and Office Facilities | Second Amendment |  |  |
Operating Leased Assets [Line Items] |  |  |
Right-of-use assets | $ 1,200 |  |
Operating lease liability | $ 1,200 |  |
Operating lease commencement month and year | 2020-08 |  |

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- Definition Indicates (true false) whether lessee has option to extend operating lease. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 842 -SubTopic 20 -Section 50 -Paragraph 3 -Subparagraph (a)(3) -URI http://asc.fasb.org/extlink&oid=123408670&loc=SL77918673-209980 + Details
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- Definition Term of lessee's operating lease renewal, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Publisher FASB -Name Accounting Standards Codification -Topic 842 -SubTopic 20 -Section 50 -Paragraph 3 -Subparagraph (a)(3) -URI http://asc.fasb.org/extlink&oid=123408670&loc=SL77918673-209980 + Details
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- Definition Amount of operating lease expense. Excludes sublease income. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Publisher FASB -Name Accounting Standards Codification -Topic 842 -SubTopic 20 -Section 45 -Paragraph 4 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=123391704&loc=SL77918638-209977 + Details
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- Definition Amount of cash outflow from operating lease, excluding payments to bring another asset to condition and location necessary for its intended use. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 842 -SubTopic 20 -Section 45 -Paragraph 5 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=123391704&loc=SL77918643-209977 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 842 -SubTopic 20 -Section 50 -Paragraph 4 -Subparagraph (g)(1) -URI http://asc.fasb.org/extlink&oid=123408670&loc=SL77918686-209980 + Details
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- Definition Weighted average remaining lease term for operating lease, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents reported fact of one year, five months, and thirteen days. + References Reference 1: http://www.xbrl.org/2003/role/exampleRef -Publisher FASB -Name Accounting Standards Codification -Topic 842 -SubTopic 20 -Section 55 -Paragraph 53 -URI http://asc.fasb.org/extlink&oid=123414884&loc=SL77918982-209971 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Publisher FASB -Name Accounting Standards Codification -Topic 842 -SubTopic 20 -Section 50 -Paragraph 4 -Subparagraph (g)(3) -URI http://asc.fasb.org/extlink&oid=123408670&loc=SL77918686-209980 + Details
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