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Subsequent Events - Additional Information (Details) $ / shares in Units, $ in Thousands |  | 1 Months Ended | 12 Months Ended
--- | --- | --- | ---
Jan. 28, 2022 GBP (£) | Jan. 31, 2022 USD ($) $ / shares shares | Dec. 31, 2021 USD ($) shares | Dec. 31, 2020 USD ($) shares | Dec. 31, 2019 USD ($)
Subsequent Event [Line Items] |  |  |  |  |
Proceeds from issuance of common stock upon public offering, net of issuance costs | $ |  |  | $ 85,990 | $ 100,664 | $ 50,321
Subsequent Event |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |
Payment of one-time option exercise fee | £ | £ 250,000 |  |  |  |
Payments for achievement of specific development and regulatory approval events | £ | £ 19,500,000 |  |  |  |
At The Market Offering | Common Stock |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |
Issuance of common stock, net of issuance costs, shares | shares |  |  | 3,407,872 | 410,896 |
At The Market Offering | Subsequent Event | Jefferies LLC | January 2021 Sales Agreement | Common Stock |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |
Issuance of common stock, net of issuance costs, shares | shares |  | 2,173 |  |  |
Proceeds from issuance of common stock upon public offering, net of issuance costs | $ |  | $ 50 |  |  |
Weighted average sales price | $ / shares |  | $ 24.01 |  |  |

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- Definition Payments for achievement of specific development and regulatory approval events. + References No definition available. + Details
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- Definition Detail information of subsequent event by type. User is expected to use existing line items from elsewhere in the taxonomy as the primary line items for this disclosure, which is further associated with dimension and member elements pertaining to a subsequent event. + References No definition available. + Details
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