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Statements of Stockholders' Equity - USD ($) $ in Thousands | Total | Follow-on Public Offering | At-the-market Offering | Common Stock | Common Stock Follow-on Public Offering | Common Stock At-the-market Offering | Additional Paid-In Capital | Additional Paid-In Capital Follow-on Public Offering | Additional Paid-In Capital At-the-market Offering | Accumulated Other Comprehensive Income (Loss) | Accumulated Deficit
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Beginning balance at Dec. 31, 2020 | $ 198,274 |  |  | $ 3 |  |  | $ 325,250 |  |  | $ 7 | $ (126,986)
Beginning balance, shares at Dec. 31, 2020 |  |  |  | 29,537,216 |  |  |  |  |  |  |
Issuance of common stock, net of issuance cost |  | $ 85,990 | $ 57,263 |  | $ 1 |  |  | $ 85,989 | $ 57,263 |  |
Issuance of common stock, net of issuance costs, shares |  |  |  |  | 5,333,333 | 3,407,872 |  |  |  |  |
Issuance of common stock upon exercise of stock options | 1,510 |  |  |  |  |  | 1,510 |  |  |  |
Issuance of common stock upon exercise of stock options, shares |  |  |  | 211,900 |  |  |  |  |  |  |
Employee stock purchase plan (ESPP) purchase | 697 |  |  |  |  |  | 697 |  |  |  |
Employee stock purchase plan (ESPP) purchase, shares |  |  |  | 50,037 |  |  |  |  |  |  |
Repurchase of unvested restricted stock |  |  |  | (7,313) |  |  |  |  |  |  |
Vesting of early exercised common stock options and restricted stock | 24 |  |  |  |  |  | 24 |  |  |  |
Stock-based compensation | 8,237 |  |  |  |  |  | 8,237 |  |  |  |
Other comprehensive gain (loss) | (719) |  |  |  |  |  |  |  |  | (719) |
Net Income (Loss) | (49,762) |  |  |  |  |  |  |  |  |  | (49,762)
Ending balance at Dec. 31, 2021 | 301,514 |  |  | $ 4 |  |  | 478,970 |  |  | (712) | (176,748)
Ending balance, shares at Dec. 31, 2021 |  |  |  | 38,533,045 |  |  |  |  |  |  |
Issuance of common stock, net of issuance cost |  | 86,081 | 8,842 |  | $ 1 |  |  | 86,080 | 8,842 |  |
Issuance of common stock, net of issuance costs, shares |  |  |  |  | 8,761,905 | 601,844 |  |  |  |  |
Issuance of common stock upon exercise of stock options | 1,448 |  |  |  |  |  | 1,448 |  |  |  |
Issuance of common stock upon exercise of stock options, shares |  |  |  | 214,643 |  |  |  |  |  |  |
Employee stock purchase plan (ESPP) purchase | 755 |  |  |  |  |  | 755 |  |  |  |
Employee stock purchase plan (ESPP) purchase, shares |  |  |  | 81,742 |  |  |  |  |  |  |
Stock-based compensation | 11,629 |  |  |  |  |  | 11,629 |  |  |  |
Other comprehensive gain (loss) | (2,159) |  |  |  |  |  |  |  |  | (2,159) |
Net Income (Loss) | (58,655) |  |  |  |  |  |  |  |  |  | (58,655)
Ending balance at Dec. 31, 2022 | 349,455 |  |  | $ 5 |  |  | 587,724 |  |  | (2,871) | (235,403)
Ending balance, shares at Dec. 31, 2022 |  |  |  | 48,193,179 |  |  |  |  |  |  |
Issuance of common stock, net of issuance cost |  | $ 281,122 | $ 28,598 |  | $ 2 |  |  | $ 281,120 | $ 28,598 |  |
Issuance of common stock, net of issuance costs, shares |  |  |  |  | 14,655,993 | 1,188,705 |  |  |  |  |
Issuance of pre-funded warrants for the purchase of common stock | 42,182 |  |  |  |  |  | 42,182 |  |  |  |
Issuance of common stock upon exercise of stock options | 9,559 |  |  |  |  |  | 9,559 |  |  |  |
Issuance of common stock upon exercise of stock options, shares |  |  |  | 931,012 |  |  |  |  |  |  |
Employee stock purchase plan (ESPP) purchase | 1,213 |  |  |  |  |  | 1,213 |  |  |  |
Employee stock purchase plan (ESPP) purchase, shares |  |  |  | 70,480 |  |  |  |  |  |  |
Stock-based compensation | 18,489 |  |  |  |  |  | 18,489 |  |  |  |
Other comprehensive gain (loss) | 3,433 |  |  |  |  |  |  |  |  | 3,433 |
Net Income (Loss) | (112,961) |  |  |  |  |  |  |  |  |  | (112,961)
Ending balance at Dec. 31, 2023 | $ 621,090 |  |  | $ 7 |  |  | $ 968,885 |  |  | $ 562 | $ (348,364)
Ending balance, shares at Dec. 31, 2023 |  |  |  | 65,039,369 |  |  |  |  |  |  |

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