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Condensed Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
 6 Months Ended
Jun. 30, 2024
Jun. 30, 2023
Cash flows from operating activities    
Net loss $ (92,344) $ (51,566)
Adjustments to reconcile net loss to net cash used in operating activities    
Depreciation and amortization 1,238 1,207
Net amortization (accretion) of premiums (discounts) on marketable securities (12,954) (4,111)
Stock-based compensation 16,046 8,390
Amortization of right-of-use assets 941 751
Changes in assets and liabilities    
Accounts receivable 17 51
Prepaid expenses and other assets (3,504) (2,508)
Accounts payable 9,243 1,589
Accrued and other liabilities 5,625 (3,260)
Contract liabilities 0 (10,935)
Lease liabilities (1,003) (910)
Net cash used in operating activities (76,695) (61,302)
Cash flows from investing activities    
Purchases of property and equipment, net (2,298) (927)
Purchases of marketable securities (640,544) (292,543)
Maturities of marketable securities 357,428 195,610
Net cash used in investing activities (285,414) (97,860)
Cash flows from financing activities    
Proceeds from issuance of common stock upon public offering, net of issuance costs 0 153,840
Proceeds from issuance of common stock related to at-the-market offering program, net of issuance costs 379,971 2,526
Proceeds from issuance of pre-funded warrants to purchase common stock, net of issuance costs 0 35,132
Proceeds from ESPP purchase 781 637
Proceeds from exercise of common stock options 7,542 1,854
Net cash provided by financing activities 388,294 193,989
Net increase in cash, cash equivalents and restricted cash 26,185 34,827
Cash, cash equivalents and restricted cash, at beginning of period 157,775 68,738
Cash, cash equivalents and restricted cash, at end of period 183,960 103,565
Reconciliation of cash, cash equivalents and restricted cash    
Cash and cash equivalents 183,049 102,843
Restricted cash 911 722
Cash, cash equivalents and restricted cash 183,960 103,565
Supplemental disclosure of cash flow information:    
Cash paid for interest 22 26
Supplemental non-cash investing and financing activities:    
Purchases of property and equipment in accounts payable and accrued liabilities 45 600
Unpaid offering costs 0 351
Unpaid at-the-market offering program costs $ 16 $ 0