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Revenue Recognition - Summary of Revenue Disaggregated by Research Program (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022
Disaggregation Of Revenue [Line Items]
Total collaboration revenue	$ 7,000	$ 23,385	$ 50,931
MAT2A Program
Disaggregation Of Revenue [Line Items]
Total collaboration revenue		3,722	29,756
Pol Theta Program
Disaggregation Of Revenue [Line Items]
Total collaboration revenue		3,002	13,894
WRN Program
Disaggregation Of Revenue [Line Items]
Total collaboration revenue	$ 7,000	$ 16,661	$ 7,281

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