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Income Taxes - Reconciliation of Effective Tax Rate to the Statutory Rate (Details) - USD ($)
$ in Thousands
3 Months Ended 12 Months Ended
Dec. 31, 2017
Sep. 30, 2017
Jun. 30, 2017
Mar. 31, 2017
Dec. 31, 2016
Sep. 30, 2016
Jun. 30, 2016
Mar. 31, 2016
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Amount                        
Income tax (benefit) expense at federal statutory rate                 $ (16,037) $ (12,192) $ (4,282) $ 9,935
State income tax, net of federal benefit                 (2,283) (1,758) (1,101) 1,295
Non-deductible warrants (income)/expense                 1,360 (481) (3,162) (2,098)
Domestic production activity                 0 0 0 (334)
Other permanent differences                 106 110 137 191
Research and development tax credits                 (426) (837) (1,632) (1,953)
Tax reserve reassessment                 104 (141) 412 246
Federal tax rate change                 10,899 0 0 0
Change in valuation allowance                 4,956 26,846 0 0
3PI Settlement                 1,976 0 0 0
Other, net                 (212) 66 (74) 462
Total tax expense (benefit) $ (320) $ 149 $ 135 $ 479 $ (1,238) $ (1,792) $ 18,000 $ (3,357) $ 443 $ 11,613 $ (9,702) $ 7,744
Percent                        
Income tax (benefit) expense at federal statutory rate                 34.00% 34.00% 34.00% 34.00%
State income tax, net of federal benefit                 4.80% 4.90% 8.70% 4.40%
Non-deductible warrants (income)/expense                 (2.90%) 1.30% 25.10% (7.20%)
Domestic production activity                 (0.00%) (0.00%) (0.00%) (1.10%)
Other permanent differences                 (0.20%) (0.30%) (1.10%) 0.70%
Research and development tax credits                 0.90% 2.30% 13.00% (6.70%)
Tax reserve reassessment                 (0.20%) 0.40% (3.30%) 0.80%
Federal tax rate change                 (23.10%) 0.00% 0.00% 0.00%
Change in valuation allowance                 (10.40%) (74.90%) 0.00% 0.00%
3PI Settlement                 (4.20%) 0.00% 0.00% 0.00%
Other, net                 0.40% (0.10%) 0.60% 1.60%
Income tax expense (benefit)                 (0.90%) (32.40%) 77.00% 26.50%