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Balance Sheet Components | 12 Months Ended
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Dec. 31, 2016
Balance Sheet Related Disclosures [Abstract] |
Balance Sheet Components | Balance Sheet Components Property and Equipment, Net Property and equipment consisted of the following (in thousands of dollars):
| Year Ended December 31,
| 2016 |  | 2015
Leasehold improvements | $ | 5,861 |  |  | $ | 789 |
Laboratory equipment | 6,441 |  |  | 5,501 |
Computer equipment | 1,177 |  |  | 1,046 |
Software, including software developed for internal use | 1,937 |  |  | 1,353 |
Furniture and fixtures | 1,131 |  |  | 242 |
Construction-in-process | 1,769 |  |  | 6,823 |
Total property and equipment, at cost | 18,316 |  |  | 15,754 |
Accumulated depreciation and amortization | (6,836 | ) |  | (5,440 | )
Total property and equipment, net | $ | 11,480 |  |  | $ | 10,314 |
Depreciation and amortization expense was $2.4 million, $1.5 million and $1.2 million for the years ended December 31, 2016, 2015 and 2014, respectively. Equipment under a capital lease was purchased in December 2016 but was not available for use at December 31, 2016, and as such, there was no amortization expense for equipment under capital lease in 2016. Accrued Liabilities Accrued liabilities consisted of the following (in thousands of dollars):
| Year Ended December 31,
| 2016 |  | 2015
Accrued compensation expense | $ | 6,120 |  |  | $ | 4,212 |
Accrued Genzyme co-promotion fees | — |  |  | 2,089 |
Accrued other | 2,990 |  |  | 2,388 |
Total accrued liabilities | $ | 9,110 |  |  | $ | 8,689 |

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