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Balance Sheet Components
 12 Months Ended
Dec. 31, 2016
Balance Sheet Related Disclosures [Abstract]  
Balance Sheet Components
Balance Sheet Components

Property and Equipment, Net

Property and equipment consisted of the following (in thousands of dollars):

 
Year Ended December 31,
 
2016
 
2015
Leasehold improvements
$
5,861

 
$
789

Laboratory equipment
6,441

 
5,501

Computer equipment
1,177

 
1,046

Software, including software developed for internal use
1,937

 
1,353

Furniture and fixtures
1,131

 
242

Construction-in-process
1,769

 
6,823

Total property and equipment, at cost
18,316

 
15,754

Accumulated depreciation and amortization
(6,836
)
 
(5,440
)
Total property and equipment, net
$
11,480

 
$
10,314



Depreciation and amortization expense was $2.4 million, $1.5 million and $1.2 million for the years ended December 31, 2016, 2015 and 2014, respectively.

Equipment under a capital lease was purchased in December 2016 but was not available for use at December 31, 2016, and as such, there was no amortization expense for equipment under capital lease in 2016.

Accrued Liabilities

Accrued liabilities consisted of the following (in thousands of dollars):

 
Year Ended December 31,
 
2016
 
2015
Accrued compensation expense
$
6,120

 
$
4,212

Accrued Genzyme co-promotion fees
—

 
2,089

Accrued other
2,990

 
2,388

Total accrued liabilities
$
9,110

 
$
8,689