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Business Combination (Details) - USD ($)
$ / shares in Units, $ in Thousands
1 Months Ended 12 Months Ended
Sep. 30, 2014
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Sep. 16, 2014
Fair value of the assets acquired and liabilities assumed:          
Goodwill   $ 1,057 $ 1,057    
Useful life   15 years      
Amortization of IPR&D   $ 1,067 800 $ 0  
Pro-Forma Financial Information          
Revenue     38,190 21,884  
Net loss     (29,090) (28,605)  
Allegro          
Business Combination          
Number of Allegro shares received for each share of common stock issued and outstanding of a wholly-owned subsidiary of the Company 1        
Conversion right, number of shares 964,377        
Conversion right, cash $ 2,700        
Outstanding indebtedness settled in cash 4,300        
Acquisition-related costs 500        
Transaction bonuses and severance payments 1,200        
Acquisition consideration          
Stock 10,078        
Cash 2,725        
Payment of outstanding indebtedness 4,290        
Total acquisition consideration 17,093        
Closing price of Company's common stock         $ 10.45
Fair value of the assets acquired and liabilities assumed:          
Cash and cash equivalents 29        
Other assets, net 7        
In-process research and development 16,000        
Goodwill 1,057        
Total acquisition consideration $ 17,093        
Discount rate (as a percent) 18.50%        
Allegro | Transaction bonus and other payments to employees and acquisition related costs          
Pro-Forma Financial Information          
Net loss     2,200    
Allegro | Interest expense related to indebtedness of acquired entity          
Pro-Forma Financial Information          
Net loss     2,300 $ 4,500  
Allegro | IPR&D          
Fair value of the assets acquired and liabilities assumed:          
Accumulated amortization   1,100 800    
Annual amortization expense expected to be recognized   1,900 $ 800    
Amortization expense over each of the next five years   $ 1,100      
Allegro | IPR&D | Maximum          
Fair value of the assets acquired and liabilities assumed:          
Useful life   15 years