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Genzyme Co-promotion Agreement (Details)
$ in Thousands
1 Months Ended 12 Months Ended 14 Months Ended 22 Months Ended 31 Months Ended
Jan. 01, 2015
Aug. 12, 2014
Feb. 29, 2012
USD ($)
Feb. 29, 2008
USD ($)
Dec. 31, 2016
USD ($)
Dec. 31, 2015
USD ($)
Dec. 31, 2014
USD ($)
Dec. 31, 2012
Feb. 27, 2014
Dec. 31, 2015
USD ($)
Aug. 11, 2014
Feb. 28, 2015
country
Jan. 31, 2012
country
Genzyme Co-promotion Agreement                          
Amortization of up-front co-promotion fee         $ 948 $ 1,897 $ 2,269            
Co-promotion agreement | Genzyme                          
Genzyme Co-promotion Agreement                          
Co-promotion expenses         6,100 7,300 12,000            
Outstanding obligation to Genzyme         0 2,100       $ 2,100      
Amortization of up-front co-promotion fee         $ 900 $ 1,900 $ 2,300            
Afirma thyroid diagnostic solution co-promotion agreement | Genzyme                          
Genzyme Co-promotion Agreement                          
Number of countries outside United States for exclusive promotion under the agreement | country                         40
Co-promotion fee received from Genzyme     $ 10,000 $ 10,000                  
Co-promotion fees as a percentage of cash receipts         15.00%     50.00% 40.00% 32.00%      
Straight-line amortization period of co-promotion fee                     4 years    
Termination notification period   6 months                      
Ex-U.S. Co-Promotion Agreement | Genzyme                          
Genzyme Co-promotion Agreement                          
Number of countries outside United States for exclusive promotion under the agreement | country                       5  
Co-promotion fee paid as a percentage of net revenue 25.00%                        
Period of agreement 5 years