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Commitments and Contingencies (Details)
ft² in Thousands, $ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2017
USD ($)
Sep. 30, 2016
USD ($)
Sep. 30, 2017
USD ($)
ft²
Sep. 30, 2016
USD ($)
Dec. 31, 2016
USD ($)
Future minimum lease payments under non-cancelable operating leases          
2017 $ 539   $ 539    
2018 2,121   2,121    
2019 2,227   2,227    
2020 2,332   2,332    
2021 2,401   2,401    
Thereafter 11,856   11,856    
Total minimum lease payments 21,476   21,476    
Facilities rent expense 469 $ 457 $ 1,400 $ 1,500  
Headquarters and laboratory facilities, South San Francisco, Lease signed April 2015          
Operating Leases          
Amount of space leased | ft²     59    
Security deposit 603   $ 603   $ 603
Laboratory facilities, Austin, Texas | Other assets          
Operating Leases          
Security deposit $ 139   $ 139   $ 75