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Note 8 - Stockholders' Equity (Tables) | 6 Months Ended
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Jun. 30, 2020
Notes Tables |
Schedule of Common Stock Capital Shares Reserved for Future Issuance [Table Text Block] |
|  | June 30, 2020 |  |  | December 31, 2019 |
Stock options and restricted stock units issued and outstanding |  |  | 5,534,822 |  |  |  | 5,562,484 |
Stock options and restricted stock units available for grant under stock option plans |  |  | 3,207,661 |  |  |  | 1,954,804 |
Common stock available for the Employee Stock Purchase Plan |  |  | 112,226 |  |  |  | 173,168 |
Total |  |  | 8,854,709 |  |  |  | 7,690,456 |

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