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Note 6 - Commitments and Contingencies (Details Textual) | 3 Months Ended | 6 Months Ended |  |
--- | --- | --- | --- | ---
Jun. 30, 2020 USD ($) | Jun. 30, 2019 USD ($) | Jun. 30, 2020 USD ($) | Jun. 30, 2019 USD ($) | Dec. 31, 2019 USD ($) | Jun. 30, 2015 a
Operating Lease, Expense | $ 500,000 | $ 500,000 | $ 1,000,000.0 | $ 1,000,000.0 |  |
Headquarters and Laboratory Facilities in South San Francisco, California [Member] |  |  |  |  |  |
Area of Real Estate Property (Acre) | a |  |  |  |  |  | 59,000
Headquarters and Laboratory Facilities in South San Francisco, California [Member] | Other Noncurrent Assets [Member] |  |  |  |  |  |
Security Deposit | 603,000 |  | 603,000 |  | $ 603,000 |
Laboratory and Office Space in Austin, Texas [Member] | Other Noncurrent Assets [Member] |  |  |  |  |  |
Security Deposit | $ 139,000 |  | $ 139,000 |  | $ 139,000 |

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