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Condensed Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Operating activities    
Net loss $ (14,461) $ (41,868)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 6,556 2,550
Stock-based compensation 6,645 3,855
Benefit from income taxes (3) (3,795)
Interest on end-of-term debt obligation 53 53
Noncash lease expense 587 258
Revaluation of acquisition-related contingent consideration 31 192
Effect of foreign currency on operations 131 82
Changes in operating assets and liabilities:    
Accounts receivable (3,575) (3,748)
Supplies and inventory (1,201) (10)
Prepaid expenses and other current assets (2,139) 132
Other assets 451 (58)
Operating lease liabilities (597) (373)
Accounts payable (960) 1,931
Accrued liabilities and deferred revenue (390) 238
Net cash used in operating activities (8,872) (40,561)
Investing activities    
Acquisition of Decipher Biosciences, net of cash acquired 0 (574,411)
Purchases of property and equipment (2,453) (1,196)
Net cash used in investing activities (2,453) (575,607)
Financing activities    
Proceeds from the issuance of common stock in a public offering, net of issuance costs 0 593,821
Payment of long-term debt (100) 0
Payment of taxes on vested restricted stock units (1,447) (6,774)
Proceeds from the exercise of common stock options and employee stock purchases 3,537 3,965
Net cash provided by financing activities 1,990 591,012
Decrease in cash, cash equivalents and restricted cash (9,335) (25,156)
Effect of foreign currency on cash, cash equivalents and restricted cash (247) 0
Net decrease in cash, cash equivalents and restricted cash (9,582) (25,156)
Cash, cash equivalents and restricted cash at beginning of period 173,946 349,967
Cash, cash equivalents and restricted cash at end of period 164,364 324,811
Supplementary cash flow information:    
Purchases of property and equipment included in accounts payable and accrued liability 342 357
Interest paid on debt 0 0
Cash and cash equivalents 163,615  
Restricted cash 749  
Total cash, cash equivalents and restricted cash $ 164,364 $ 324,811