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Pay vs Performance Disclosure - USD ($)

12 Months Ended

Dec. 31, 2024

Dec. 31, 2023

Dec. 31, 2022

Dec. 31, 2021

Dec. 31, 2020

Pay vs Performance Disclosure

Pay vs Performance Disclosure, Table

			Year			Summary Compensation Table Total for Marc Stapley ($)(1)			Summary Compensation Table Total for Bonnie Anderson ($)(1)			Compensation Actually Paid to Marc Stapley ($)(1)(2)(3)			Compensation Actually Paid to Bonnie Anderson ($)(1)(2)(3)			Average Summary Compensation Table Total for Non-PEO NEOs ($)(1)			Average Compensation Actually Paid to Non-PEO NEOs ($)(1)(2)(3)			Value of Initial Fixed $100 Investment based on:(4)						Net Income ($ in millions)			Total Revenue ($ in millions)(⁵)
																								TSR ($)			Peer Group TSR ($)
																								2024			6,816,368									—			14,888,998			—			3,154,952			6,617,801			141.83			118.20			24.1			445.8
			2023			7,184,634			—			9,559,060			—			2,742,803			3,440,029			98.53			118.87			(74.4)			361.1
			2022			4,935,422			—			1,622,674			—			3,725,476			1,450,011			84.99			113.65			(36.6)			296.5
			2021			5,741,940			4,518,093			5,700,065			2,876,781			2,235,504			(434,017)			147.56			126.45			(75.6)			219.5
			2020			—			4,571,345			—			15,466,734			2,200,189			5,837,075			175.29			126.42			(34.9)			117.5

Company Selected Measure Name

Total Revenue

Named Executive Officers, Footnote

Bonnie Anderson was our PEO until June 2021. Marc Stapley has been our PEO from June 2021 to present. The individuals comprising the Non-PEO NEOs for each year presented are listed below.

2020

2021

2022

2023 - 2024

Keith Kennedy

Keith Kennedy

Giulia Kennedy

Rebecca Chambers

Giulia Kennedy

Giulia Kennedy

Rebecca Chambers

Phillip Febbo

John Hanna

James Erlinger III

Tina Nova

John Leite

James Erlinger III

Beverly Jane Alley

Annie McGuire

Annie McGuire

Rebecca Chambers

Peer Group Issuers, Footnote

The Peer Group TSR set forth in this table utilizes the NASDAQ Biotechnology Index, which we also utilize in the stock performance graph required by Item 201(e) of Regulation S-K included in our Annual Report for the year ended December 31, 2024. The comparison assumes $100 was invested for the period starting December 31, 2019, through the end of the listed year in the company and in the NASDAQ Biotechnology Index, respectively. Historical stock performance is not necessarily indicative of future stock performance.

PEO Total Compensation Amount

$ 6,816,368

PEO Actually Paid Compensation Amount

$ 14,888,998

Adjustment To PEO Compensation, Footnote

Compensation Actually Paid reflects the exclusions and inclusions of certain amounts for the PEOs and the Non-PEO NEOs as set forth below. Equity values are calculated in accordance with FASB ASC Topic 718. Amounts in the Exclusion of Stock Awards and Option Awards column below reflect the totals from the Stock Awards and Option Awards columns set forth in the Summary Compensation Table.

			Year			Summary Compensation Table Total for Marc Stapley ($)			Exclusion of Stock Awards and Option Awards for Marc Stapley ($)			Inclusion of Equity Values for Marc Stapley ($)			Compensation Actually Paid to Marc Stapley ($)
			2024			6,816,368			(5,125,868)			13,198,498			14,888,998

			Year			Average Summary Compensation Table Total for Non-PEO NEOs ($)						Average Exclusion of Stock Awards and Option Awards for Non-PEO NEOs ($)						Average Inclusion of Equity Values for Non-PEO NEOs ($)			Average Compensation Actually Paid to Non-PEO NEOs ($)
			2024			3,154,952						(2,228,638)						5,691,487			6,617,801

The amounts in the Inclusion of Equity Values in the tables above are derived from the amounts set forth in the following tables:

			Year			Year-End Fair Value of Equity Awards Granted During Year That Remained Unvested as of Last Day of Year for Marc Stapley ($)			Change in Fair Value from Last Day of Prior Year to Last Day of Year of Unvested Equity Awards for Marc Stapley ($)			Vesting-Date Fair Value of Equity Awards Granted During Year that Vested During Year for Marc Stapley ($)			Change in Fair Value from Last Day of Prior Year to Vesting Date of Unvested Equity Awards that Vested During Year for Marc Stapley ($)			Fair Value at Last Day of Prior Year of Equity Awards Forfeited During Year for Marc Stapley ($)			Total - Inclusion of Equity Values for Marc Stapley ($)
			2024			9,086,140			4,361,025			—			(248,667)			—			13,198,498

			Year			Average Year-End Fair Value of Equity Awards Granted During Year That Remained Unvested as of Last Day of Year for Non-PEO NEOs ($)			Average Change in Fair Value from Last Day of Prior Year to Last Day of Year of Unvested Equity Awards for Non-PEO NEOs ($)			Average Vesting-Date Fair Value of Equity Awards Granted During Year that Vested During Year for Non-PEO NEOs ($)			Average Change in Fair Value from Last Day of Prior Year to Vesting Date of Unvested Equity Awards that Vested During Year for Non-PEO NEOs ($)			Average Fair Value at Last Day of Prior Year of Equity Awards Forfeited During Year for Non-PEO NEOs ($)			Total - Average Inclusion of Equity Values for Non-PEO NEOs ($)
			2024			3,950,496			1,682,964			—			58,027			—			5,691,487

Non-PEO NEO Average Total Compensation Amount

$ 3,154,952

$ 2,742,803

$ 3,725,476

$ 2,235,504

$ 2,200,189

Non-PEO NEO Average Compensation Actually Paid Amount

$ 6,617,801

3,440,029

1,450,011

(434,017)

5,837,075

Adjustment to Non-PEO NEO Compensation Footnote

Compensation Actually Paid reflects the exclusions and inclusions of certain amounts for the PEOs and the Non-PEO NEOs as set forth below. Equity values are calculated in accordance with FASB ASC Topic 718. Amounts in the Exclusion of Stock Awards and Option Awards column below reflect the totals from the Stock Awards and Option Awards columns set forth in the Summary Compensation Table.

			Year			Summary Compensation Table Total for Marc Stapley ($)			Exclusion of Stock Awards and Option Awards for Marc Stapley ($)			Inclusion of Equity Values for Marc Stapley ($)			Compensation Actually Paid to Marc Stapley ($)
			2024			6,816,368			(5,125,868)			13,198,498			14,888,998

			Year			Average Summary Compensation Table Total for Non-PEO NEOs ($)						Average Exclusion of Stock Awards and Option Awards for Non-PEO NEOs ($)						Average Inclusion of Equity Values for Non-PEO NEOs ($)			Average Compensation Actually Paid to Non-PEO NEOs ($)
			2024			3,154,952						(2,228,638)						5,691,487			6,617,801

The amounts in the Inclusion of Equity Values in the tables above are derived from the amounts set forth in the following tables:

			Year			Year-End Fair Value of Equity Awards Granted During Year That Remained Unvested as of Last Day of Year for Marc Stapley ($)			Change in Fair Value from Last Day of Prior Year to Last Day of Year of Unvested Equity Awards for Marc Stapley ($)			Vesting-Date Fair Value of Equity Awards Granted During Year that Vested During Year for Marc Stapley ($)			Change in Fair Value from Last Day of Prior Year to Vesting Date of Unvested Equity Awards that Vested During Year for Marc Stapley ($)			Fair Value at Last Day of Prior Year of Equity Awards Forfeited During Year for Marc Stapley ($)			Total - Inclusion of Equity Values for Marc Stapley ($)
			2024			9,086,140			4,361,025			—			(248,667)			—			13,198,498

			Year			Average Year-End Fair Value of Equity Awards Granted During Year That Remained Unvested as of Last Day of Year for Non-PEO NEOs ($)			Average Change in Fair Value from Last Day of Prior Year to Last Day of Year of Unvested Equity Awards for Non-PEO NEOs ($)			Average Vesting-Date Fair Value of Equity Awards Granted During Year that Vested During Year for Non-PEO NEOs ($)			Average Change in Fair Value from Last Day of Prior Year to Vesting Date of Unvested Equity Awards that Vested During Year for Non-PEO NEOs ($)			Average Fair Value at Last Day of Prior Year of Equity Awards Forfeited During Year for Non-PEO NEOs ($)			Total - Average Inclusion of Equity Values for Non-PEO NEOs ($)
			2024			3,950,496			1,682,964			—			58,027			—			5,691,487

Compensation Actually Paid vs. Total Shareholder Return

The following charts show the relationship between Compensation Actually Paid, Total Stockholder Return, total revenue and net loss for 2020, 2021, 2022, 2023 and 2024.

Compensation Actually Paid vs. Net Income

The following charts show the relationship between Compensation Actually Paid, Total Stockholder Return, total revenue and net loss for 2020, 2021, 2022, 2023 and 2024.

Compensation Actually Paid vs. Company Selected Measure

The following charts show the relationship between Compensation Actually Paid, Total Stockholder Return, total revenue and net loss for 2020, 2021, 2022, 2023 and 2024.

Total Shareholder Return Vs Peer Group

The following charts show the relationship between Compensation Actually Paid, Total Stockholder Return, total revenue and net loss for 2020, 2021, 2022, 2023 and 2024.

Tabular List, Table

Total Revenue

Ending Cash Balance

Gross Margin on Testing Revenue

Total Shareholder Return Amount

$ 141.83

98.53

84.99

147.56

175.29

Peer Group Total Shareholder Return Amount

118.20

118.87

113.65

126.45

126.42

Net Income (Loss)

$ 24,100,000

$ (74,400,000)

$ (36,600,000)

$ (75,600,000)

$ (34,900,000)

Company Selected Measure Amount

445,800,000

361,100,000

296,500,000

219,500,000

117,500,000

Additional 402(v) Disclosure

The amounts shown for Compensation Actually Paid have been calculated in accordance with Item 402(v) of Regulation S-K and do not reflect compensation actually earned, realized, or received by the company’s NEOs. These amounts reflect the Summary Compensation Table Total with certain adjustments as described in footnote 3 below.We determined Total Revenue to be the most important financial performance measure used to link company performance to Compensation Actually Paid to our PEOs and Non-PEO NEOs in 2024. This performance measure may not have been the most important financial performance measure in prior years, and we may determine a different financial performance measure to be the most important financial performance measure in future years.

Measure:: 1

Pay vs Performance Disclosure

Name

Total Revenue

Measure:: 2

Pay vs Performance Disclosure

Name

Ending Cash Balance

Measure:: 3

Pay vs Performance Disclosure

Name

Gross Margin on Testing Revenue

Stapley [Member]

Pay vs Performance Disclosure

PEO Total Compensation Amount

$ 6,816,368

$ 7,184,634

$ 4,935,422

$ 5,741,940

PEO Actually Paid Compensation Amount

$ 14,888,998

$ 9,559,060

$ 1,622,674

$ 5,700,065

PEO Name

Marc Stapley

Marc Stapley

Marc Stapley

Marc Stapley

Anderson [Member]

Pay vs Performance Disclosure

PEO Total Compensation Amount

$ 4,518,093

$ 4,571,345

PEO Actually Paid Compensation Amount

$ 2,876,781

$ 15,466,734

PEO Name

Bonnie Anderson

Bonnie Anderson

PEO | Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table

Pay vs Performance Disclosure

Adjustment to Compensation, Amount

$ (5,125,868)

PEO | Equity Awards Adjustments, Excluding Value Reported in Compensation Table

Pay vs Performance Disclosure

Adjustment to Compensation, Amount

13,198,498

PEO | Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested

Pay vs Performance Disclosure

Adjustment to Compensation, Amount

9,086,140

PEO | Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested

Pay vs Performance Disclosure

Adjustment to Compensation, Amount

4,361,025

PEO | Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year

Pay vs Performance Disclosure

Adjustment to Compensation, Amount

0

PEO | Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year

Pay vs Performance Disclosure

Adjustment to Compensation, Amount

(248,667)

PEO | Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year

Pay vs Performance Disclosure

Adjustment to Compensation, Amount

0

Non-PEO NEO | Aggregate Grant Date Fair Value of Equity Award Amounts Reported in Summary Compensation Table

Pay vs Performance Disclosure

Adjustment to Compensation, Amount

(2,228,638)

Non-PEO NEO | Equity Awards Adjustments, Excluding Value Reported in Compensation Table

Pay vs Performance Disclosure

Adjustment to Compensation, Amount

5,691,487

Non-PEO NEO | Year-end Fair Value of Equity Awards Granted in Covered Year that are Outstanding and Unvested

Pay vs Performance Disclosure

Adjustment to Compensation, Amount

3,950,496

Non-PEO NEO | Year-over-Year Change in Fair Value of Equity Awards Granted in Prior Years That are Outstanding and Unvested

Pay vs Performance Disclosure

Adjustment to Compensation, Amount

1,682,964

Non-PEO NEO | Vesting Date Fair Value of Equity Awards Granted and Vested in Covered Year

Pay vs Performance Disclosure

Adjustment to Compensation, Amount

0

Non-PEO NEO | Change in Fair Value as of Vesting Date of Prior Year Equity Awards Vested in Covered Year

Pay vs Performance Disclosure

Adjustment to Compensation, Amount

58,027

Non-PEO NEO | Prior Year End Fair Value of Equity Awards Granted in Any Prior Year that Fail to Meet Applicable Vesting Conditions During Covered Year

Pay vs Performance Disclosure

Adjustment to Compensation, Amount

$ 0

X

- References

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-Number 229
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- Definition

The portion of profit or loss for the period, net of income taxes, which is attributable to the parent.

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