<SEC-DOCUMENT>0001193125-25-319642.txt : 20251215
<SEC-HEADER>0001193125-25-319642.hdr.sgml : 20251215
<ACCEPTANCE-DATETIME>20251215195225
ACCESSION NUMBER:		0001193125-25-319642
CONFORMED SUBMISSION TYPE:	144
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20251215
DATE AS OF CHANGE:		20251215

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Disc Medicine, Inc.
		CENTRAL INDEX KEY:			0001816736
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		ORGANIZATION NAME:           	03 Life Sciences
		EIN:				851612845
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		144
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	001-39438
		FILM NUMBER:		251573021

	BUSINESS ADDRESS:	
		STREET 1:		321 ARSENAL STREET, SUITE 101
		CITY:			WATERTOWN
		STATE:			MA
		ZIP:			02472
		BUSINESS PHONE:		(617) 674-9274

	MAIL ADDRESS:	
		STREET 1:		321 ARSENAL STREET, SUITE 101
		CITY:			WATERTOWN
		STATE:			MA
		ZIP:			02472

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Gemini Therapeutics, Inc. /DE
		DATE OF NAME CHANGE:	20210209

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	FS Development Corp.
		DATE OF NAME CHANGE:	20200702

REPORTING-OWNER:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			AI DMI LLC
		CENTRAL INDEX KEY:			0001890993
		ORGANIZATION NAME:           	
		EIN:				000000000
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		144

	BUSINESS ADDRESS:	
		STREET 1:		C/O ACCESS INDUSTRIES, INC.
		STREET 2:		40 WEST 57TH STREET, 28TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10019
		BUSINESS PHONE:		212-247-6400

	MAIL ADDRESS:	
		STREET 1:		C/O ACCESS INDUSTRIES, INC.
		STREET 2:		40 WEST 57TH STREET, 28TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10019
</SEC-HEADER>
<DOCUMENT>
<TYPE>144
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/ownership" xmlns:xsd="http://www.w3.org/2001/XMLSchema" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
<headerData>
<submissionType>144</submissionType>
<filerInfo>
<filer>
<filerCredentials>
<cik>0001890993</cik>
<ccc>XXXXXXXX</ccc>
</filerCredentials>
</filer>
<liveTestFlag>LIVE</liveTestFlag>
</filerInfo>
</headerData>
<formData>
<issuerInfo>
<issuerCik>0001816736</issuerCik>
<issuerName>Disc Medicine, Inc.</issuerName>
<secFileNumber>001-39438</secFileNumber>
<issuerAddress>
<street1 xmlns="http://www.sec.gov/edgar/common">321 Arsenal Street</street1>
<street2 xmlns="http://www.sec.gov/edgar/common">Suite 101</street2>
<city xmlns="http://www.sec.gov/edgar/common">Watertown</city>
<stateOrCountry xmlns="http://www.sec.gov/edgar/common">MA</stateOrCountry>
<zipCode xmlns="http://www.sec.gov/edgar/common">02472</zipCode>
</issuerAddress>
<issuerContactPhone>617-674-9274</issuerContactPhone>
<nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>AI DMI LLC</nameOfPersonForWhoseAccountTheSecuritiesAreToBeSold>
<relationshipsToIssuer>
<relationshipToIssuer>Affiliate</relationshipToIssuer>
</relationshipsToIssuer>
</issuerInfo>
<securitiesInformation>
<securitiesClassTitle>Common Stock</securitiesClassTitle>
<brokerOrMarketmakerDetails>
<name>Tourmaline Partners, LLC</name>
<address>
<street1 xmlns="http://www.sec.gov/edgar/common">680 Washington Boulevard</street1>
<street2 xmlns="http://www.sec.gov/edgar/common">10th Floor</street2>
<city xmlns="http://www.sec.gov/edgar/common">Stamford</city>
<stateOrCountry xmlns="http://www.sec.gov/edgar/common">CT</stateOrCountry>
<zipCode xmlns="http://www.sec.gov/edgar/common">06901</zipCode>
</address>
</brokerOrMarketmakerDetails>
<noOfUnitsSold>5843</noOfUnitsSold>
<aggregateMarketValue>537556.00</aggregateMarketValue>
<noOfUnitsOutstanding>37750162</noOfUnitsOutstanding>
<approxSaleDate>12/15/2025</approxSaleDate>
<securitiesExchangeName>NASDAQ</securitiesExchangeName>
</securitiesInformation>
<securitiesToBeSold>
<securitiesClassTitle>Common Stock</securitiesClassTitle>
<acquiredDate>12/29/2022</acquiredDate>
<natureOfAcquisitionTransaction>Conversion of Shares in Connection with Merger*</natureOfAcquisitionTransaction>
<nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
<isGiftTransaction>N</isGiftTransaction>
<amountOfSecuritiesAcquired>2706976</amountOfSecuritiesAcquired>
<paymentDate>12/29/2022</paymentDate>
<natureOfPayment>Conversion of Shares in Connection with Merger*</natureOfPayment>
</securitiesToBeSold>
<securitiesToBeSold>
<securitiesClassTitle>Common Stock</securitiesClassTitle>
<acquiredDate>02/15/2023</acquiredDate>
<natureOfAcquisitionTransaction>Purchase of Common Stock</natureOfAcquisitionTransaction>
<nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
<isGiftTransaction>N</isGiftTransaction>
<amountOfSecuritiesAcquired>434783</amountOfSecuritiesAcquired>
<paymentDate>02/15/2023</paymentDate>
<natureOfPayment>Cash</natureOfPayment>
</securitiesToBeSold>
<securitiesToBeSold>
<securitiesClassTitle>Common Stock</securitiesClassTitle>
<acquiredDate>06/17/2024</acquiredDate>
<natureOfAcquisitionTransaction>Purchase of Common Stock</natureOfAcquisitionTransaction>
<nameOfPersonfromWhomAcquired>Issuer</nameOfPersonfromWhomAcquired>
<isGiftTransaction>N</isGiftTransaction>
<amountOfSecuritiesAcquired>416667</amountOfSecuritiesAcquired>
<paymentDate>06/17/2024</paymentDate>
<natureOfPayment>Cash</natureOfPayment>
</securitiesToBeSold>
<nothingToReportFlagOnSecuritiesSoldInPast3Months>N</nothingToReportFlagOnSecuritiesSoldInPast3Months>
<securitiesSoldInPast3Months>
<sellerDetails>
<name>AI DMI LLC</name>
<address>
<street1 xmlns="http://www.sec.gov/edgar/common">C/O ACCESS INDUSTRIES, INC.</street1>
<street2 xmlns="http://www.sec.gov/edgar/common">40 WEST 57TH STREET, 28TH FLOOR</street2>
<city xmlns="http://www.sec.gov/edgar/common">NEW YORK</city>
<stateOrCountry xmlns="http://www.sec.gov/edgar/common">NY</stateOrCountry>
<zipCode xmlns="http://www.sec.gov/edgar/common">10019</zipCode>
</address>
</sellerDetails>
<securitiesClassTitle>Common Stock</securitiesClassTitle>
<saleDate>10/22/2025</saleDate>
<amountOfSecuritiesSold>744047</amountOfSecuritiesSold>
<grossProceeds>59873462.09</grossProceeds>
</securitiesSoldInPast3Months>
<securitiesSoldInPast3Months>
<sellerDetails>
<name>AI DMI LLC</name>
<address>
<street1 xmlns="http://www.sec.gov/edgar/common">C/O ACCESS INDUSTRIES, INC.</street1>
<street2 xmlns="http://www.sec.gov/edgar/common">40 WEST 57TH STREET, 28TH FLOOR</street2>
<city xmlns="http://www.sec.gov/edgar/common">NEW YORK</city>
<stateOrCountry xmlns="http://www.sec.gov/edgar/common">NY</stateOrCountry>
<zipCode xmlns="http://www.sec.gov/edgar/common">10019</zipCode>
</address>
</sellerDetails>
<securitiesClassTitle>Common Stock</securitiesClassTitle>
<saleDate>12/12/2025</saleDate>
<amountOfSecuritiesSold>29388</amountOfSecuritiesSold>
<grossProceeds>2715547.44</grossProceeds>
</securitiesSoldInPast3Months>
<remarks>*Shares to be sold were acquired through conversion in connection with a merger.</remarks>
<noticeSignature>
<noticeDate>12/15/2025</noticeDate>
<signature>Langhorne S. Perrow</signature>
</noticeSignature>
</formData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
