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v3.25.4

Consolidated Statements of Cash Flows - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2025 | Dec. 31, 2024 | Dec. 31, 2023
CASH FLOWS FROM OPERATING ACTIVITIES: |  |  |
Net loss | $ (16,141) | $ (140,039) | $ (262,140)
Adjustments to reconcile net loss to net cash used in operating activities: |  |  |
Stock-based compensation expense | 40,364 | 41,730 | 38,813
Amortization of intangible assets | 4,667 | 1,959 | 750
Non-cash interest expense | 1,756 | 5,404 | 4,030
Net accretion on marketable securities | (2,094) | (6,901) | (6,989)
Other non-cash items, net | 652 | 769 | 1,980
Changes in operating assets and liabilities: |  |  |
Accounts receivable, net | (73,163) | (47,259) | (17,349)
Inventories | (7,329) | (400) | (5,620)
Prepaid expenses and other current assets | (2,007) | (948) | (8,621)
Accounts payable | (1,694) | 2,229 | 3,152
Accrued liabilities | 50,044 | 32,033 | 5,594
Operating lease liabilities | (680) | (735) | (657)
Net cash used in operating activities | (5,625) | (112,158) | (247,057)
CASH FLOWS FROM INVESTING ACTIVITIES: |  |  |
Purchases of marketable securities | (246,986) | (254,820) | (225,840)
Proceeds from maturities and sales of marketable securities | 227,419 | 288,783 | 406,500
Purchases of property and equipment | (686) | (143) | (428)
Milestone payment for intangible asset | (10,000) | (5,000) | 0
Net cash provided by (used in) investing activities | (30,253) | 28,820 | 180,232
CASH FLOWS FROM FINANCING ACTIVITIES: |  |  |
Proceeds from issuance of common stock, net of issuance costs | 0 | 161,682 | 0
Repayment of long-term debt | 0 | (100,000) | 0
Proceeds from issuance of common stock upon exercise of stock options | 4,597 | 2,807 | 1,247
Proceeds from issuance of common stock for ESPP | 2,376 | 1,713 | 1,175
Proceeds from issuance of common stock and pre-funded warrants, net of issuance costs | 0 | 0 | 95,765
Proceeds from issuance of shares under ATM, net of issuance costs | 0 | 0 | 3,136
Net cash provided by financing activities | 6,973 | 66,202 | 101,323
Effect of exchange rate changes on cash | 168 | (235) | (50)
Net increase (decrease) in cash, cash equivalents and restricted cash | (28,737) | (17,371) | 34,448
Cash, cash equivalents and restricted cash at beginning of period | 71,952 | 89,323 | 54,875
Cash, cash equivalents and restricted cash at end of period | 43,215 | 71,952 | 89,323
SUPPLEMENTAL DISCLOSURES OF NON-CASH INVESTING AND FINANCING INFORMATION: |  |  |
Right-of-use assets obtained in exchange for operating lease liabilities | 2,858 | 0 | 0
SUPPLEMENTAL DISCLOSURES OF CASH FLOW INFORMATION: |  |  |
Interest expense paid in cash | $ 10,327 | $ 22,209 | $ 25,445

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