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Segment Reporting | 12 Months Ended
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Dec. 31, 2025
Segment Reporting [Abstract] |
Segment Reporting | Segment Reporting The Company has one reportable segment relating to the development and commercialization of treatments for dermatological diseases. The Company’s Chief Operating Decision Maker (CODM) is its Chief Executive Officer. The CODM evaluates financial information on a consolidated basis for the purposes of allocating resources and assessing performance. Substantially all of the Company's assets are located in the United States. The table below is a summary of the segment profit or loss, including significant segment expenses (in thousands):
| Year Ended December 31,
| 2025 |  | 2024 |  | 2023
Total revenues | $ | 376,072 |  |  | $ | 196,542 |  |  | $ | 59,606 |
Less: |  |  |  |  |
Cost of sales | 32,028 |  |  | 17,169 |  |  | 4,237 |
Topical roflumilast program costs | 10,938 |  |  | 5,210 |  |  | 35,607 |
Topical JAK inhibitor program costs | 741 |  |  | 2,945 |  |  | 3,334 |
Other early-stage programs costs | 6,372 |  |  | 11,477 |  |  | 5,681 |
Research and development compensation and personnel-related expenses | 39,779 |  |  | 39,216 |  |  | 44,613 |
Selling, general and administrative expenses | 274,033 |  |  | 228,908 |  |  | 184,628 |
Other segment expenses(1) | 24,408 |  |  | 20,014 |  |  | 22,607 |
Total operating expenses | 388,299 |  |  | 324,939 |  |  | 300,707 |
Operating loss | (12,227) |  |  | (128,397) |  |  | (241,101) |
Interest income | 8,897 |  |  | 16,126 |  |  | 12,517 |
Interest expense | (12,083) |  |  | (27,168) |  |  | (29,712) |
Other income (expense), net | 443 |  |  | 47 |  |  | (731) |
Provision for income taxes | 1,171 |  |  | 647 |  |  | 3,113 |
Segment and consolidated net loss | $ | (16,141) |  |  | $ | (140,039) |  |  | $ | (262,140) |
(1) Other segment expenses include professional services related to research and development, medical affairs, depreciation and amortization expenses.

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- Definition The entire disclosure for reporting segments including data and tables. Reportable segments include those that meet any of the following quantitative thresholds a) it's reported revenue, including sales to external customers and intersegment sales or transfers is 10 percent or more of the combined revenue, internal and external, of all operating segments b) the absolute amount of its reported profit or loss is 10 percent or more of the greater, in absolute amount of 1) the combined reported profit of all operating segments that did not report a loss or 2) the combined reported loss of all operating segments that did report a loss c) its assets are 10 percent or more of the combined assets of all operating segments. + References Reference 1: http://www.xbrl.org/2003/role/disclosureRef -Topic 280 -SubTopic 10 -Name Accounting Standards Codification -Section 50 -Paragraph 21 -Subparagraph (b) -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-21 Reference 2: http://www.xbrl.org/2003/role/disclosureRef -Topic 280 -SubTopic 10 -Name 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