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Segment Reporting (Tables)

12 Months Ended

Dec. 31, 2025

Segment Reporting [Abstract]

Schedule of Segment Reporting Information, by Segment

The table below is a summary of the segment profit or loss, including significant segment expenses (in thousands):

			Year Ended December 31,
			2025						2024						2023
Total revenues			$	376,072					$	196,542					$	59,606
Less:
Cost of sales			32,028						17,169						4,237
Topical roflumilast program costs			10,938						5,210						35,607
Topical JAK inhibitor program costs			741						2,945						3,334
Other early-stage programs costs			6,372						11,477						5,681
Research and development compensation and personnel-related expenses			39,779						39,216						44,613
Selling, general and administrative expenses			274,033						228,908						184,628
Other segment expenses(1)			24,408						20,014						22,607
Total operating expenses			388,299						324,939						300,707
Operating loss			(12,227)						(128,397)						(241,101)
Interest income			8,897						16,126						12,517
Interest expense			(12,083)						(27,168)						(29,712)
Other income (expense), net			443						47						(731)
Provision for income taxes			1,171						647						3,113
Segment and consolidated net loss			$	(16,141)					$	(140,039)					$	(262,140)

(1) Other segment expenses include professional services related to research and development, medical affairs, depreciation and amortization expenses.

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- Definition

Tabular disclosure of the profit or loss and total assets for each reportable segment. An entity discloses certain information on each reportable segment if the amounts (a) are included in the measure of segment profit or loss reviewed by the chief operating decision maker or (b) are otherwise regularly provided to the chief operating decision maker, even if not included in that measure of segment profit or loss.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 25
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482810/280-10-50-25

Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 22
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482810/280-10-50-22

Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef
-Name Accounting Standards Codification
-Topic 280
-SubTopic 10
-Section 50
-Paragraph 30
-Publisher FASB
-URI https://asc.fasb.org/1943274/2147482810/280-10-50-30

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X

- References

No definition available.

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