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Stockholders' Equity - Narrative (Details)
$ / shares in Units, $ in Thousands
1 Months Ended 12 Months Ended
Jan. 01, 2026
shares
Jan. 01, 2025
shares
Feb. 28, 2024
USD ($)
Feb. 13, 2024
shares
Jan. 16, 2024
shares
Jan. 01, 2024
shares
May 06, 2021
USD ($)
Jan. 30, 2020
shares
Jan. 31, 2024
USD ($)
Dec. 31, 2023
USD ($)
shares
Oct. 31, 2023
USD ($)
$ / shares
shares
Nov. 30, 2022
shares
Aug. 31, 2016
Dec. 31, 2025
USD ($)
$ / shares
shares
Dec. 31, 2024
USD ($)
$ / shares
shares
Dec. 31, 2023
USD ($)
$ / shares
shares
Oct. 31, 2025
shares
Dec. 31, 2022
shares
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Capital stock                           310,000,000        
Common stock, par value (in dollars per share) | $ / shares                           $ 0.0001 $ 0.0001      
Common stock, shares authorized (in shares)                           300,000,000 300,000,000      
Preferred stock, shares authorized (in shares)                           10,000,000        
Preferred stock, shares outstanding (in shares)                           0 0      
Proceeds from issuance of common stock, net of issuance costs | $     $ 161,700                     $ 0 $ 161,682 $ 0    
Forfeited (in shares)                           534,345        
Intrinsic value of options exercised during the period | $                           $ 10,000 4,200 1,200    
Total grant-date fair value of the options vested | $                           $ 8,500 $ 4,000 $ 28,000    
Weighted-average grant-date fair value (in dollars per share) | $ / shares                           $ 9.94 $ 3.70 $ 8.01    
Total stock-based compensation expense | $                           $ 40,364 $ 41,730 $ 38,813    
Stock Options                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Unrecognized compensation cost | $                           $ 25,700        
Recognition period for unrecognized compensation costs related to unvested options expected to vest (in years)                           2 years 7 months 6 days        
Dividend yield                           0.00% 0.00% 0.00%    
RSUs subject to future vesting                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Vesting period of stock-based awards granted (in share)                           4 years        
Granted (in shares)                           3,063,418        
Total grant-date fair value | $                           $ 18,800 $ 17,400 $ 9,300    
Unrecognized compensation cost | $                           $ 47,500        
Recognition period for unrecognized compensation costs related to unvested options expected to vest (in years)                           2 years 9 months 18 days        
Employee Stock Purchase Plan                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Increase in shares available for grant, percentage of shares outstanding (as a percent)               1.00%                    
Purchase price of common stock, as a percentage of closing trading price per share (as a percent)               85.00%                    
Total stock-based compensation expense | $                           $ 1,000 $ 900 $ 900    
Employee Stock Purchase Plan | Common Stock                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Number of additional shares authorized (in shares)   1,178,480       967,873                        
Shares available for grant (in shares)                           2,806,818        
Number of shares authorized for sale under the ESPP (in shares)               351,000                    
Maximum shares to be issued               5,265,000                    
Restricted Stock | First anniversary date                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Vesting rights, percentage                         25.00%          
Subsequent Event | Employee Stock Purchase Plan | Common Stock                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Number of additional shares authorized (in shares) 1,216,890                                  
2020 Equity Incentive Plan                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Common stock reserved (in shares)               2,134,000                    
Increase in shares available for grant, percentage of shares outstanding (as a percent)               4.00%                    
Based number of options issuable (in shares)               11,000,000                    
Number of additional shares authorized (in shares)   4,713,921       3,871,494                        
Shares available for grant (in shares)                           4,093,603        
Dividend yield                           0.00%        
2020 Equity Incentive Plan | Stock Options                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Vesting period of stock-based awards granted (in share)                           4 years        
2020 Equity Incentive Plan | Subsequent Event                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Number of additional shares authorized (in shares) 4,933,306                                  
2017 Equity Incentive Plan                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Common stock reserved (in shares)               1,550,150                    
2022 Employment Inducement Incentive Plan                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Common stock reserved (in shares)                                   1,250,000
Number of additional shares authorized (in shares)                       1,500,000            
Shares available for grant (in shares)                           111,533        
Stock Option Exchange | Stock Options                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Percentage of eligible options exchanged         98.00%                          
Stock Option Exchange | RSUs subject to future vesting                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Incremental cost of plan modification | $                           $ 8,600        
Stock Option Exchange | RSUs subject to future vesting | Minimum                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Award requisite service period (in years)                           1 year        
Stock Option Exchange | RSUs subject to future vesting | Maximum                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Award requisite service period (in years)                           3 years        
Stock Option Exchange | RSUs subject to future vesting | Grant Date One                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Vesting period of stock-based awards granted (in share)       1 year                            
Stock Option Exchange | RSUs subject to future vesting | Second Grant Date                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Vesting period of stock-based awards granted (in share)       2 years                            
Stock Option Exchange | RSUs subject to future vesting | Third Grant Date                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Vesting period of stock-based awards granted (in share)       3 years                            
Common Stock | Stock Option Exchange | Stock Options                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Forfeited (in shares)         5,059,129                          
Common Stock | Stock Option Exchange | RSUs subject to future vesting                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Granted (in shares)       2,129,594                            
Prefunded Warrant                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Warrants to acquire shares of common stock (in shares)                   1,417,808 7,500,000     6,941,438 7,500,000 1,417,808 2,285,000  
Stock price (in dollars per share) | $ / shares                     $ 2.4999              
Exercise price (in dollars per share) | $ / shares                     $ 0.0001              
Warrants outstanding (in shares)                           5,215,000        
First Equity Public Offering                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Proceeds from issuance of common stock, net of issuance costs | $                     $ 95,800              
At-The-Market | Common Stock                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Issuance of shares of common stock for sales agreement | $                 $ 100,000                  
At-The-Market | Cowen | Common Stock                                    
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]                                    
Proceeds from issuance of common stock, net of issuance costs | $                   $ 3,100                
Stock price (in dollars per share) | $ / shares                             $ 2.60      
Number of shares issued in transaction (in shares)                   1,250,000                
Issuance of shares of common stock for sales agreement | $             $ 100,000                      
Share sales agreement, percentage of gross sales price (as a percent)             0.03