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Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2025
Dec. 31, 2024
Dec. 31, 2023
CASH FLOWS FROM OPERATING ACTIVITIES:      
Net loss $ (16,141) $ (140,039) $ (262,140)
Adjustments to reconcile net loss to net cash used in operating activities:      
Stock-based compensation expense 40,364 41,730 38,813
Amortization of intangible assets 4,667 1,959 750
Non-cash interest expense 1,756 5,404 4,030
Net accretion on marketable securities (2,094) (6,901) (6,989)
Other non-cash items, net 652 769 1,980
Changes in operating assets and liabilities:      
Accounts receivable, net (73,163) (47,259) (17,349)
Inventories (7,329) (400) (5,620)
Prepaid expenses and other current assets (2,007) (948) (8,621)
Accounts payable (1,694) 2,229 3,152
Accrued liabilities 50,044 32,033 5,594
Operating lease liabilities (680) (735) (657)
Net cash used in operating activities (5,625) (112,158) (247,057)
CASH FLOWS FROM INVESTING ACTIVITIES:      
Purchases of marketable securities (246,986) (254,820) (225,840)
Proceeds from maturities and sales of marketable securities 227,419 288,783 406,500
Purchases of property and equipment (686) (143) (428)
Milestone payment for intangible asset (10,000) (5,000) 0
Net cash provided by (used in) investing activities (30,253) 28,820 180,232
CASH FLOWS FROM FINANCING ACTIVITIES:      
Proceeds from issuance of common stock, net of issuance costs 0 161,682 0
Repayment of long-term debt 0 (100,000) 0
Proceeds from issuance of common stock upon exercise of stock options 4,597 2,807 1,247
Proceeds from issuance of common stock for ESPP 2,376 1,713 1,175
Proceeds from issuance of common stock and pre-funded warrants, net of issuance costs 0 0 95,765
Proceeds from issuance of shares under ATM, net of issuance costs 0 0 3,136
Net cash provided by financing activities 6,973 66,202 101,323
Effect of exchange rate changes on cash 168 (235) (50)
Net increase (decrease) in cash, cash equivalents and restricted cash (28,737) (17,371) 34,448
Cash, cash equivalents and restricted cash at beginning of period 71,952 89,323 54,875
Cash, cash equivalents and restricted cash at end of period 43,215 71,952 89,323
SUPPLEMENTAL DISCLOSURES OF NON-CASH INVESTING AND FINANCING INFORMATION:      
Right-of-use assets obtained in exchange for operating lease liabilities 2,858 0 0
SUPPLEMENTAL DISCLOSURES OF CASH FLOW INFORMATION:      
Interest expense paid in cash $ 10,327 $ 22,209 $ 25,445