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v3.26.1

Statements of Cash Flows - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2025 | Dec. 31, 2024
Cash flows from operating activities: |  |
Net loss | $ (177,042) | $ (111,779)
Adjustments to reconcile net loss to net cash and cash equivalents used in operations: |  |
Depreciation | 167 | 130
Stock-based compensation | 21,383 | 6,988
Amortization of debt issuance costs and discount | 3,137 | 1,331
Payment-in-kind interest | 1,104 | 1,364
Non-cash operating lease expense | (7) |
Change in accrued interest income | 630 | 150
Changes in operating assets and liabilities: |  |
Prepaid clinical trial costs | (12,127) | (1,994)
Other current and non-current assets | (2,991) | 2,770
Accounts payable | (3,040) | 4,316
Accrued clinical trial costs | 118 | 10,244
Other accrued expenses | 15,388 | 3,013
Net cash used in operating activities | (153,280) | (83,467)
Cash flows from investing activities: |  |
Proceeds from maturities of investments | 332,507 | 642,346
Purchases of investments | (396,342) | (705,165)
Purchases of property and equipment | (249) | (250)
Net cash used in investing activities | (64,084) | (63,069)
Cash flows from financing activities: |  |
Proceeds from employee stock purchases | 711 | 276
Proceeds from exercise of common stock options | 3,485 | 770
Proceeds from exercise of common stock warrants | 42,061 | 14,736
Proceeds from convertible debt, net of debt issuance costs of $6,246 and $0 during the years ended December 31, 2025 and 2024, respectively | 195,004 |
Proceeds from note payable, net of debt issuance costs of $2,255 and $2,438 during the years ended December 31, 2025 and 2024, respectively | 27,745 | 59,226
Proceeds from equity offering, net of underwriting discounts and offering costs | 91,592 | 56,252
Proceeds from an ATM offering, net of issuance costs |  | 7,356
Payments for secondary registration statement costs | (46) | (228)
Net cash provided by financing activities | 360,552 | 138,388
Net change in cash and cash equivalents | 143,188 | (8,148)
Cash and cash equivalents: |  |
Beginning of period | 22,515 | 30,663
End of period | 165,703 | 22,515
Supplemental disclosure of cash flow information: |  |
Cash paid for interest | 10,348 | 7,586
Cash paid for operating leases | 220 | 325
Supplemental disclosures of non-cash investing and financing activities: |  |
Common stock warrants issued with the note payable transaction | 2,786 | 1,229
Property and equipment included in accounts payable | 82 | 1
Deferred financing, offering and registration statement costs included in accounts payable |  | $ 42

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