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v3.22.1

Consolidated Statements of Cash Flows $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2021 USD ($) | Dec. 31, 2020 USD ($)
Cash flows from operating activities: |  |
Net loss | $ (90,122) | $ (49,499)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Stock-based compensation | 8,678 | 3,807
Amortization of premium on available-for-sale securities | 865 | 268
Amortization of debt issuance costs and accretion of final payment fee | 617 | 230
Depreciation | 79 | 60
Deferred tax assets | (150) | (69)
Changes in operating assets and liabilities: |  |
Prepaid and other current assets | (5,672) | (3,600)
Accounts payable | 4,778 | 1,131
Accrued expenses | 4,146 | 1,428
Net cash used in operating activities | (76,781) | (46,244)
Cash flows from investing activities: |  |
Proceeds from sales and maturities of available-for-sale securities | 148,422 | 12,189
Purchases of available-for-sale securities | (141,200) | (118,895)
Purchases of property and equipment | (63) | (126)
Net cash provided by (used in) investing activities | 7,159 | (106,832)
Cash flows from financing activities: |  |
Proceeds from term loan facility, net of issuance costs | 19,951 |
Proceeds from issuance of common stock upon public offerings,net of issuance costs | 3,289 | 157,680
Proceeds from issuance of common stock upon stock option exercises | 487 | 271
Payment of debt issuance costs |  | (161)
Net cash provided by financing activities | 23,871 | 157,924
Net change in cash and cash equivalents, and restricted cash | (45,751) | 4,848
Cash and cash equivalents, and restricted cash at beginning of period | 98,208 | 93,360
Cash and cash equivalents, and restricted cash at end of period | 52,457 | 98,208
Components of cash and cash equivalents, and restricted cash: |  |
Cash and cash equivalents | 52,432 | 98,183
Restricted cash | 25 | 25
Total cash and cash equivalents, and restricted cash | 52,457 | 98,208
Supplemental disclosures of cash information: |  |
Cash paid for interest | 16 |
Cash paid for income taxes |  | 142
Supplemental disclosures of noncash information: |  |
Issuance of common stock warrant in connection with term loan facility | 574 | 634
ESPP Purchases |  |
Cash flows from financing activities: |  |
Proceeds from issuance of common stock upon ESPP purchases | $ 144 | $ 134

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