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Commitments and Contingencies - Additional Information (Details) - USD ($) | 1 Months Ended | 3 Months Ended | 6 Months Ended
--- | --- | --- | ---
Apr. 30, 2018 | Jun. 30, 2022 | Jun. 30, 2021 | Jun. 30, 2022 | Jun. 30, 2021
Loss Contingencies [Line Items] |  |  |  |  |
Operating leases, rent expense |  | $ 47,000 | $ 72,000 | $ 100,000 | $ 100,000
Remaining lease term |  | 6 months |  | 6 months |
Incremental borrowing rate used to determine operating lease liability percentage |  |  |  | 4.25% |
Teva Agreement |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |
Payment upon achievement of certain clinical and commercial milestones | $ 135,000,000.0 |  |  |  |
Asset transfer and license agreement, termination period after written notice |  |  |  | 120 days |
Asset transfer and license agreement, termination period notice of breach |  |  |  | 60 days |
Asset transfer and license agreement termination notice period if bankruptcy petition filed |  |  |  | 60 days |
Teva Agreement | Research and Development Expenses |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |
Milestone payments |  | $ 0 | $ 0 | $ 0 | $ 0
Teva Agreement | Teva's GlycoPEGylated FGF21 Program |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |
Payment upon achievement of certain clinical and commercial milestones | 67,500,000 |  |  |  |
Teva Agreement | Teva's Development Program |  |  |  |  |
Loss Contingencies [Line Items] |  |  |  |  |
Payment upon achievement of certain clinical and commercial milestones | $ 67,500,000 |  |  |  |

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