<SEC-DOCUMENT>0000947871-22-000741-index.html : 20220705
<SEC-HEADER>0000947871-22-000741.hdr.sgml : 20220705
<ACCEPTANCE-DATETIME>20220705163035
ACCESSION NUMBER:		0000947871-22-000741
CONFORMED SUBMISSION TYPE:	SC 13D/A
PUBLIC DOCUMENT COUNT:		2
FILED AS OF DATE:		20220705
DATE AS OF CHANGE:		20220705
GROUP MEMBERS:		ORBIMED ADVISORS ISRAEL II LTD
GROUP MEMBERS:		ORBIMED CAPITAL GP VI LLC
GROUP MEMBERS:		ORBIMED ISRAEL GP II, L.P.

SUBJECT COMPANY:	

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			89bio, Inc.
		CENTRAL INDEX KEY:			0001785173
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				831114349
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		SC 13D/A
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	005-91200
		FILM NUMBER:		221065370

	BUSINESS ADDRESS:	
		STREET 1:		142 SANSOME STREET
		STREET 2:		SECOND FLOOR
		CITY:			SAN FRANCISCO
		STATE:			CA
		ZIP:			94104
		BUSINESS PHONE:		(415) 432-9270

	MAIL ADDRESS:	
		STREET 1:		142 SANSOME STREET
		STREET 2:		SECOND FLOOR
		CITY:			SAN FRANCISCO
		STATE:			CA
		ZIP:			94104

FILED BY:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ORBIMED ADVISORS LLC
		CENTRAL INDEX KEY:			0001055951
		IRS NUMBER:				133976876
		STATE OF INCORPORATION:			DE

	FILING VALUES:
		FORM TYPE:		SC 13D/A

	BUSINESS ADDRESS:	
		STREET 1:		601 LEXINGTON AVENUE
		STREET 2:		54TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022
		BUSINESS PHONE:		(212) 739-6400

	MAIL ADDRESS:	
		STREET 1:		601 LEXINGTON AVENUE
		STREET 2:		54TH FLOOR
		CITY:			NEW YORK
		STATE:			NY
		ZIP:			10022
</SEC-HEADER>
<DOCUMENT>
<TYPE>SC 13D/A
<SEQUENCE>1
<FILENAME>ss1139058_sc13da.htm
<DESCRIPTION>AMENDMENT NO. 3
<TEXT>
Document 1 - file: ss1139058_sc13da.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.1
<SEQUENCE>2
<FILENAME>ss1139058_ex9901.htm
<DESCRIPTION>JOINT FILING AGREEMENT
<TEXT>
Document 2 - file: ss1139058_ex9901.htm

</DOCUMENT>
</SEC-DOCUMENT>