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Stockholders' Equity - Additional Information (Details) - USD ($) $ / shares in Units, $ in Thousands |  | 1 Months Ended | 2 Months Ended | 12 Months Ended
--- | --- | --- | --- | ---
Feb. 15, 2023 | Jul. 31, 2022 | Mar. 31, 2021 | Feb. 28, 2023 | Dec. 31, 2022 | Dec. 31, 2021
Subsidiary Sale Of Stock [Line Items] |  |  |  |  |  |
Proceeds from issuance of common stock, net of commissions and offering expenses |  |  |  |  | $ 50 | $ 144
Common stock, par value |  |  |  |  | $ 0.001 | $ 0.001
Pre-funded Warrants |  |  |  |  |  |
Subsidiary Sale Of Stock [Line Items] |  |  |  |  |  |
Percentage of ownership limitation |  | 9.99% |  |  |  |
Percentage of ownership prior to issuance |  | 4.99% |  |  |  |
Warrants |  |  |  |  |  |
Subsidiary Sale Of Stock [Line Items] |  |  |  |  |  |
Percentage of ownership limitation |  | 9.99% |  |  |  |
Percentage of ownership prior to issuance |  | 4.99% |  |  |  |
Maximum | Pre-funded Warrants |  |  |  |  |  |
Subsidiary Sale Of Stock [Line Items] |  |  |  |  |  |
Percentage of ownership limitation |  | 19.99% |  |  |  |
Maximum | Warrants |  |  |  |  |  |
Subsidiary Sale Of Stock [Line Items] |  |  |  |  |  |
Percentage of ownership limitation |  | 19.99% |  |  |  |
A T M Facility |  |  |  |  |  |
Subsidiary Sale Of Stock [Line Items] |  |  |  |  |  |
Public offering description |  |  |  |  | In January and February 2023, the Company received aggregate proceeds of $13.4 million, net of commissions from sales of 968,000 shares of its common stock pursuant to the ATM Facility (see Note 7). |
A T M Facility | Subsequent Event |  |  |  |  |  |
Subsidiary Sale Of Stock [Line Items] |  |  |  |  |  |
Proceeds from issuance of common stock, net of commissions and offering expenses |  |  |  | $ 13,400 |  |
Shares issued and sold |  |  |  | 968,000 |  |
Public Offerings |  |  |  |  |  |
Subsidiary Sale Of Stock [Line Items] |  |  |  |  |  |
Proceeds from issuance of common stock, net of commissions and offering expenses |  | $ 88,200 |  |  |  |
Public offering description |  | In July 2022, the Company completed an underwritten public offering of its common stock, warrants to purchase shares of its common stock and pre-funded warrants to purchase shares of its common stock. The Company sold 18,675,466 shares of its common stock with accompanying warrants to purchase up to 9,337,733 shares of its common stock at a combined public offering price of $3.55 per share. The Company also sold 7,944,252 pre-funded warrants to purchase shares of its common stock with accompanying warrants to purchase up to 3,972,126 shares of its common stock at a combined public offering price of $3.549 per pre-funded warrant, which represents the per share public offering price for the common stock less $0.001 per share, the exercise price for each pre-funded warrant. The Company raised net proceeds of $88.2 million, after deducting underwriting discounts and commissions of $5.7 million and other offering costs of $0.6 million. |  |  |  |
Shares issued and sold |  | 18,675,466 |  |  |  |
Offering price per share |  | $ 3.55 |  |  |  |
Underwriting discounts and commissions |  | $ 5,700 |  |  |  |
Other offering costs |  | $ 600 |  |  |  |
Common stock, par value |  | $ 0.001 |  |  |  |
Public Offerings | Pre-funded Warrants |  |  |  |  |  |
Subsidiary Sale Of Stock [Line Items] |  |  |  |  |  |
Number of prefunded warrants issued during period |  | 7,944,252 |  |  |  |
Combined price of prefunded and common stock warrant |  | $ 3.549 |  |  |  |
Public Offerings | Maximum |  |  |  |  |  |
Subsidiary Sale Of Stock [Line Items] |  |  |  |  |  |
Warrants to purchase shares of common stock |  | 9,337,733 |  |  |  |
Public Offerings | Maximum | Pre-funded Warrants |  |  |  |  |  |
Subsidiary Sale Of Stock [Line Items] |  |  |  |  |  |
Warrants to purchase shares of common stock |  | 3,972,126 |  |  |  |
Public Offerings | A T M Facility | Maximum |  |  |  |  |  |
Subsidiary Sale Of Stock [Line Items] |  |  |  |  |  |
Maximum amount of equity shares issuable |  |  | $ 75,000 |  |  |
Public Offerings | A T M Facility | Maximum | Subsequent Event |  |  |  |  |  |
Subsidiary Sale Of Stock [Line Items] |  |  |  |  |  |
Maximum amount of equity shares issuable | $ 150,000 |  |  |  |  |
Public Offerings | SVB Leerink LLC |  |  |  |  |  |
Subsidiary Sale Of Stock [Line Items] |  |  |  |  |  |
Selling commission per shares sold percentage |  |  | 3.00% |  |  |
Proceeds from issuance of common stock, net of commissions and offering expenses |  |  |  |  | $ 28,500 | $ 3,300
Shares issued and sold |  |  |  |  | 3,948,611 | 186,546

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