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v3.22.4

Consolidated Statements of Cash Flows - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2022 | Dec. 31, 2021
Cash flows from operating activities: |  |
Net loss | $ (102,026) | $ (90,122)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Stock-based compensation | 10,356 | 8,678
Net (accretion) amortization on available-for-sale securities | (980) | 865
Amortization of debt issuance costs and accretion of final payment fee | 764 | 617
Non-cash operating lease expense | 175 |
Depreciation | 65 | 79
Deferred tax assets | 0 | (150)
Changes in operating assets and liabilities: |  |
Prepaid and other current assets | 3,331 | (5,672)
Accounts payable | 5,659 | 4,778
Accrued expenses | 1,750 | 4,146
Operating lease liability | (184) |
Net cash used in operating activities | (81,090) | (76,781)
Cash flows from investing activities: |  |
Proceeds from sales and maturities of available-for-sale securities | 118,760 | 148,422
Purchases of available-for-sale securities | (152,696) | (141,200)
Purchases of property and equipment | (7) | (63)
Net cash (used in) provided by investing activities | (33,943) | 7,159
Cash flows from financing activities: |  |
Proceeds from issuance of common stock and warrants in public offering, net of issuance costs | 88,239 |
Proceeds from issuance of common stock in at-the-market public offering, net of issuance costs | 28,453 | 3,289
Proceeds from issuance of common stock upon exercise of warrants | 1,082 |
Proceeds from issuance of common stock upon exercise of stock options | 305 | 487
Proceeds from issuance of common stock upon ESPP purchases | 50 | 144
Payment of withholding taxes related to restricted stock units | (298) |
Proceeds from term loan facility, net of issuance costs |  | 19,951
Net cash provided by financing activities | 117,831 | 23,871
Net change in cash and cash equivalents, and restricted cash | 2,798 | (45,751)
Cash and cash equivalents, and restricted cash at beginning of period | 52,457 | 98,208
Cash and cash equivalents, and restricted cash at end of period | 55,255 | 52,457
Components of cash and cash equivalents, and restricted cash: |  |
Cash and cash equivalents | 55,255 | 52,432
Restricted cash | 0 | 25
Total cash and cash equivalents, and restricted cash | 55,255 | 52,457
Supplemental disclosures of cash information: |  |
Cash paid for interest | 1,076 | 16
Cash paid for operating leases | 234 |
Supplemental disclosures of noncash information: |  |
Remeasurement of lease liability and right of use asset in connection with lease modification | $ 338 |
Issuance of common stock warrant in connection with term loan facility |  | $ 574

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