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Stockholders' Equity - Additional Information (Details) - USD ($)
$ / shares in Units, $ in Thousands
1 Months Ended 2 Months Ended 12 Months Ended
Feb. 15, 2023
Jul. 31, 2022
Mar. 31, 2021
Feb. 28, 2023
Dec. 31, 2022
Dec. 31, 2021
Subsidiary Sale Of Stock [Line Items]            
Proceeds from issuance of common stock, net of commissions and offering expenses         $ 50 $ 144
Common stock, par value         $ 0.001 $ 0.001
Pre-funded Warrants            
Subsidiary Sale Of Stock [Line Items]            
Percentage of ownership limitation   9.99%        
Percentage of ownership prior to issuance   4.99%        
Warrants            
Subsidiary Sale Of Stock [Line Items]            
Percentage of ownership limitation   9.99%        
Percentage of ownership prior to issuance   4.99%        
Maximum | Pre-funded Warrants            
Subsidiary Sale Of Stock [Line Items]            
Percentage of ownership limitation   19.99%        
Maximum | Warrants            
Subsidiary Sale Of Stock [Line Items]            
Percentage of ownership limitation   19.99%        
A T M Facility            
Subsidiary Sale Of Stock [Line Items]            
Public offering description         In January and February 2023, the Company received aggregate proceeds of $13.4 million, net of commissions from sales of 968,000 shares of its common stock pursuant to the ATM Facility (see Note 7).  
A T M Facility | Subsequent Event            
Subsidiary Sale Of Stock [Line Items]            
Proceeds from issuance of common stock, net of commissions and offering expenses       $ 13,400    
Shares issued and sold       968,000    
Public Offerings            
Subsidiary Sale Of Stock [Line Items]            
Proceeds from issuance of common stock, net of commissions and offering expenses   $ 88,200        
Public offering description   In July 2022, the Company completed an underwritten public offering of its common stock, warrants to purchase shares of its common stock and pre-funded warrants to purchase shares of its common stock. The Company sold 18,675,466 shares of its common stock with accompanying warrants to purchase up to 9,337,733 shares of its common stock at a combined public offering price of $3.55 per share. The Company also sold 7,944,252 pre-funded warrants to purchase shares of its common stock with accompanying warrants to purchase up to 3,972,126 shares of its common stock at a combined public offering price of $3.549 per pre-funded warrant, which represents the per share public offering price for the common stock less $0.001 per share, the exercise price for each pre-funded warrant. The Company raised net proceeds of $88.2 million, after deducting underwriting discounts and commissions of $5.7 million and other offering costs of $0.6 million.        
Shares issued and sold   18,675,466        
Offering price per share   $ 3.55        
Underwriting discounts and commissions   $ 5,700        
Other offering costs   $ 600        
Common stock, par value   $ 0.001        
Public Offerings | Pre-funded Warrants            
Subsidiary Sale Of Stock [Line Items]            
Number of prefunded warrants issued during period   7,944,252        
Combined price of prefunded and common stock warrant   $ 3.549        
Public Offerings | Maximum            
Subsidiary Sale Of Stock [Line Items]            
Warrants to purchase shares of common stock   9,337,733        
Public Offerings | Maximum | Pre-funded Warrants            
Subsidiary Sale Of Stock [Line Items]            
Warrants to purchase shares of common stock   3,972,126        
Public Offerings | A T M Facility | Maximum            
Subsidiary Sale Of Stock [Line Items]            
Maximum amount of equity shares issuable     $ 75,000      
Public Offerings | A T M Facility | Maximum | Subsequent Event            
Subsidiary Sale Of Stock [Line Items]            
Maximum amount of equity shares issuable $ 150,000          
Public Offerings | SVB Leerink LLC            
Subsidiary Sale Of Stock [Line Items]            
Selling commission per shares sold percentage     3.00%      
Proceeds from issuance of common stock, net of commissions and offering expenses         $ 28,500 $ 3,300
Shares issued and sold         3,948,611 186,546