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Consolidated Statements of Operations and Comprehensive Loss - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Operating expenses:    
Research and development $ 80,796 $ 70,330
General and administrative 21,453 19,413
Total operating expenses 102,249 89,743
Loss from operations (102,249) (89,743)
Interest expense (1,922) (674)
Interest income and other, net 2,164 148
Net loss before income tax (102,007) (90,269)
Income tax (expense) benefit (19) 147
Net loss (102,026) (90,122)
Other comprehensive (loss) income:    
Unrealized loss on available-for-sale securities (299) (71)
Foreign currency translation adjustments 13 17
Total other comprehensive loss (286) (54)
Comprehensive loss $ (102,312) $ (90,176)
Net loss per share, basic $ (2.93) $ (4.48)
Net loss per share, diluted $ (2.93) $ (4.48)
Weighted-average shares used to compute net loss per share, basic 34,806,349 20,098,340
Weighted-average shares used to compute net loss per share, diluted 34,806,349 20,098,340