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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands | 6 Months Ended
--- | ---
Jun. 30, 2024 | Jun. 30, 2023
Cash flows from operating activities: |  |
Net loss | $ (99,652) | $ (67,229)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Stock-based compensation | 10,167 | 7,688
Net accretion of discounts on investments in marketable securities | (5,406) | (2,188)
Amortization of debt discount and accretion of deferred debt costs | 330 | 456
Loss on extinguishment of debt |  | 1,208
Noncash operating lease expense | 351 | 83
Depreciation | 21 | 24
Other | 113 |
Changes in operating assets and liabilities: |  |
Prepaid and other assets | (14,319) | (5,816)
Accounts payable | 9,002 | (1,787)
Accrued expenses | (1,410) | 3,112
Operating lease liabilities | (91) | (83)
Other noncurrent liabilities | 10 |
Net cash used in operating activities | (100,884) | (64,532)
Cash flows from investing activities: |  |
Proceeds from sales and maturities of marketable securities | 178,090 | 82,880
Purchases of marketable securities | (230,139) | (180,582)
Net cash used in investing activities | (52,049) | (97,702)
Cash flows from financing activities: |  |
Proceeds from issuance of common stock in public offerings, net of issuance costs |  | 296,817
Payments of deferred offering costs | (116) |
Proceeds from issuance of common stock in at-the-market public offerings, net of issuance costs | 21,049 | 37,089
Proceeds from term loan facility, net of issuance costs |  | 24,363
Proceeds from issuance of common stock upon exercise of common stock warrants | 29,543 | 15,590
Proceeds from issuance of common stock upon exercise of stock options | 61 | 512
Proceeds from issuance of common stock under employee stock purchase plan | 178 | 142
Payments for taxes related to net share settlement upon vesting of restricted stock units | (1,725) | (693)
Repayment of term loan |  | (21,400)
Net cash provided by financing activities | 48,990 | 352,420
Net change in cash and cash equivalents | (103,943) | 190,186
Cash and cash equivalents at beginning of period | 316,161 | 55,255
Cash and cash equivalents at end of period | 212,218 | 245,441
Supplemental disclosures of cash information: |  |
Cash paid for interest | 1,368 | 1,198
Cash paid for amounts included in the measurement of lease liabilities | $ 239 | 93
Supplemental disclosures of noncash information: |  |
Issuance of common stock warrants in connection with term loan |  | $ 482

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