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Select Condensed Consolidated Balance Sheet Details - Accrued Expenses (Details) - USD ($) $ in Thousands | Mar. 31, 2017 | Dec. 31, 2016
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Balance Sheet Related Disclosures [Abstract] |  |
Commissions and sales milestones | $ 4,156 | $ 4,202
Payroll and payroll related | 2,419 | 2,384
Litigation settlements | 4,400 | 4,400
Globus related accruals | 767 | 3,830
Accrued professional fees | 2,308 | 3,093
Royalties | 1,350 | 1,347
Restructuring and severance accruals | 1,619 | 1,328
Accrued taxes | 419 | 404
Guaranteed collaboration compensation, current | 4,661 | 2,228
Accrued interest | 388 | 387
Other | 3,686 | 3,986
Total accrued expenses | $ 26,173 | $ 27,589

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