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Organization and Significant Accounting Policies (Tables) | 12 Months Ended
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Dec. 31, 2022
Accounting Policies [Abstract] |
Computation of Basic and Diluted Loss Per Share | The following table sets forth the computation of basic and diluted loss per share (in thousands, except per share data):
|  | Year Ended December 31, |
|  | 2022 |  |  | 2021 |  |  | 2020 |
Numerator: |  |  |  |  |  |  |  |  |
Net loss |  | $ | (152,149 | ) |  | $ | (144,326 | ) |  | $ | (78,994 | )
Denominator: |  |  |  |  |  |  |  |  |
Weighted average common shares outstanding |  |  | 103,373 |  |  |  | 96,197 |  |  |  | 67,020 |
Net loss per share, basic and diluted |  | $ | (1.47 | ) |  | $ | (1.50 | ) |  | $ | (1.18 | )
Anti-Dilutive Securities of Common Stock Excluded from Calculation of Diluted Net Loss Per Share | The following potentially dilutive shares of common stock were excluded from the calculation of diluted net loss per share because their effect would have been anti-dilutive for the years presented (in thousands):
|  | Year Ended December 31, |
|  | 2022 |  |  | 2021 |  |  | 2020 |
Series A convertible preferred stock |  |  | — |  |  |  | 29 |  |  |  | 29 |
Options to purchase common stock and employee stock purchase plan |  |  | 2,991 |  |  |  | 3,416 |  |  |  | 3,951 |
Unvested restricted stock units |  |  | 8,533 |  |  |  | 8,703 |  |  |  | 8,216 |
Warrants to purchase common stock |  |  | 15,491 |  |  |  | 20,184 |  |  |  | 24,881 |
Senior convertible notes |  |  | 17,246 |  |  |  | 17,246 |  |  |  | — |
|  |  | 44,261 |  |  |  | 49,578 |  |  |  | 37,077 |

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- Definition Tabular disclosure of securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) in the future that were not included in the computation of diluted EPS because to do so would increase EPS amounts or decrease loss per share amounts for the period presented, by antidilutive securities. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (c) -URI https://asc.fasb.org/extlink&oid=124432515&loc=d3e3550-109257 + Details
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- Definition Tabular disclosure of an entity's basic and diluted earnings per share calculations, including a reconciliation of numerators and denominators of the basic and diluted per-share computations for income from continuing operations. + References Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef -Publisher FASB -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (a) -URI https://asc.fasb.org/extlink&oid=124432515&loc=d3e3550-109257 + Details
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