XML 48 R36.htm IDEA: XBRL DOCUMENT
v3.25.3

Segment Reporting (Tables) | 9 Months Ended
--- | ---
Sep. 30, 2025
Segment Reporting |
Schedule of information about the Company's single segment | ​
​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
​ | ​ | Three Months Ended | ​ | Nine Months Ended
​ | ​ | September 30, | ​ | September 30,
​ | ​ | 2025 |  | 2024 |  | 2025 |  | 2024
Revenue | ​ | $ | 14,544 | ​ | $ | 15,425 | ​ | $ | 38,701 | ​ | $ | 46,641
Cost of product revenue | ​ | ​ | 1,774 | ​ | ​ | 1,561 | ​ | ​ | 4,980 | ​ | ​ | 4,396
Research and development (a) | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Direct program expenses | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
AXPAXLI for wet AMD | ​ | ​ | 34,707 | ​ | ​ | 17,017 | ​ | ​ | 92,893 | ​ | ​ | 35,263
Other clinical and preclinical programs | ​ | ​ | 1,224 | ​ | ​ | 1,184 | ​ | ​ | 3,307 | ​ | ​ | 6,750
Unallocated expenses | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​ | ​
Personnel costs | ​ | ​ | 9,136 | ​ | ​ | 7,551 | ​ | ​ | 27,825 | ​ | ​ | 22,168
All other costs | ​ | ​ | 1,632 | ​ | ​ | 6,365 | ​ | ​ | 5,986 | ​ | ​ | 8,815
Selling and marketing (a) | ​ | ​ | 11,721 | ​ | ​ | 9,601 | ​ | ​ | 36,972 | ​ | ​ | 27,997
General and administrative (a) | ​ | ​ | 8,563 | ​ | ​ | 8,832 | ​ | ​ | 26,864 | ​ | ​ | 28,294
Facilities (b) | ​ | ​ | 1,722 | ​ | ​ | 1,713 | ​ | ​ | 5,230 | ​ | ​ | 5,416
Stock-based compensation | ​ | ​ | 11,691 | ​ | ​ | 6,641 | ​ | ​ | 31,825 | ​ | ​ | 25,912
Depreciation | ​ | ​ | 1,072 | ​ | ​ | 958 | ​ | ​ | 3,076 | ​ | ​ | 2,835
Interest income | ​ | ​ | 3,729 | ​ | ​ | 5,653 | ​ | ​ | 11,012 | ​ | ​ | 15,611
Interest expense | ​ | ​ | (3,002) | ​ | ​ | (3,224) | ​ | ​ | (9,003) | ​ | ​ | (10,471)
Loss from debt extinguishment | ​ | ​ | — | ​ | ​ | — | ​ | ​ | — | ​ | ​ | (27,950)
Other non-operating items | ​ | ​ | (1,447) | ​ | ​ | 7,076 | ​ | ​ | (3,037) | ​ | ​ | (1,103)
Net loss | ​ | $ | (69,418) | ​ | $ | (36,493) | ​ | $ | (201,285) | ​ | $ | (145,118)
​
| (a) | excluding stock-based compensation, depreciation, and facilities expenses
| (b) | excluding stock-based compensation and depreciation

X
- Definition Tabular disclosure of the profit or loss and total assets for each reportable segment. An entity discloses certain information on each reportable segment if the amounts (a) are included in the measure of segment profit or loss reviewed by the chief operating decision maker or (b) are otherwise regularly provided to the chief operating decision maker, even if not included in that measure of segment profit or loss. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 25 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-25 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 22 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-22 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 30 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-30 + Details
Name: | us-gaap_ScheduleOfSegmentReportingInformationBySegmentTextBlock
Namespace Prefix: | us-gaap_
Data Type: | dtr-types:textBlockItemType
Balance Type: | na
Period Type: | duration

X
- References No definition available. + Details
Name: | us-gaap_SegmentReportingAbstract
Namespace Prefix: | us-gaap_
Data Type: | xbrli:stringItemType
Balance Type: | na
Period Type: | duration