Exhibit 12.1 – Statement of Ratios of Earnings to Fixed Charges

Enterprise Financial Services Corp
Statement Regarding Computation of Ratios of Earnings to Fixed Charges (unaudited)
($ in thousands)

    Nine Months                    
  Ended                  
  September 30, Years ended December 31,
       2008      2007      2006      2005      2004      2003
Including Interest on Deposits:                                   
     Earnings (1):                      
     Income before income tax expense $ 13,107     $ 26,594   $ 24,672   $ 17,720   $ 12,303   $ 10,950  
     Fixed charges   39,294   61,466     43,141     23,541     12,169     10,544  
     Other adjustments (2)      -        -       (875 )     (113 )        -          -  
     Total earnings (a) $ 52,401     $ 88,060     $ 66,939     $ 41,149     $ 24,472     $ 21,494  
 
     Fixed charges (1):                      
     Interest on deposits $ 30,580     $ 52,864   $ 37,832   $ 20,475   $ 9,998   $ 8,201  
     Interest on borrowings   8,713   8,601       5,309       3,067       2,170       2,343  
     Total fixed charges (b) $ 39,294     $ 61,466     $ 43,141     $ 23,541     $ 12,169     $ 10,544  
 
     Ratio of earnings to fixed charges (a/b)   1.33x   1.43x     1.55x     1.75x     2.01x     2.04x  
 
Excluding Interest on Deposits:                       
     Earnings, excluding interest on deposits:                      
     Total earnings $ 52,401     $ 88,060   $ 66,939   $ 41,149   $ 24,472   $ 21,494  
     Less interest on deposits    (30,580 )  (52,864 )      (37,832 )      (20,475 )      (9,998 )      (8,201 )
     Total earnings excluding interest on deposits (c) $ 21,821     $ 35,195     $ 29,107     $ 20,674     $ 14,474     $ 13,293  
 
     Fixed charges, excluding interest on deposits:                      
     Total fixed charges $ 39,294     $ 61,466   $ 43,141   $ 23,541   $ 12,169   $ 10,544  
     Less interest on deposits   (30,580 ) (52,864 )     (37,832 )     (20,475 )     (9,998 )     (8,201 )
     Total fixed charges, excluding interest on deposits (d)   $ 8,713     $ 8,601     $ 5,309     $ 3,067     $ 2,170     $ 2,343  
 
Ratio of earnings to fixed charges, 
     excluding interest on deposits (c/d) (3)
  2.50x   4.09x     5.48x     6.74x     6.67x     5.67x  
____________________

(1)      As defined in Item 503(d) of Regulation S-K.
 
(2) For purposes of the "earnings" computation, other adjustments include subtracting minority interest in pre-tax income of subsidiaries that have not incurred fixed charges.
 
(3)      The ratio of earnings to fixed charges, excluding interest on deposits, is being provided as an additional measure to provide comparability to the ratios disclosed by all other issuers of debt securities.