    <SEC-DOCUMENT>0001025835-21-000023-index.html : 20210317
    <SEC-HEADER>0001025835-21-000023.hdr.sgml : 20210317
    <ACCEPTANCE-DATETIME>20210317164500
    ACCESSION NUMBER:		0001025835-21-000023
    CONFORMED SUBMISSION TYPE:	DEF 14A
    PUBLIC DOCUMENT COUNT:		4
    CONFORMED PERIOD OF REPORT:	20210317
    FILED AS OF DATE:		20210317
    DATE AS OF CHANGE:		20210317

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			ENTERPRISE FINANCIAL SERVICES CORP
    		CENTRAL INDEX KEY:			0001025835
    		STANDARD INDUSTRIAL CLASSIFICATION:	STATE COMMERCIAL BANKS [6022]
    		IRS NUMBER:				431706259
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		DEF 14A
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-15373
    		FILM NUMBER:		21751113

    	BUSINESS ADDRESS:
    		STREET 1:		150 NORTH MERAMEC
    		STREET 2:		150 NORTH MERAMEC
    		CITY:			CLAYTON
    		STATE:			MO
    		ZIP:			63105
    		BUSINESS PHONE:		3147255500

    	MAIL ADDRESS:
    		STREET 1:		150 NORTH MERAMEC
    		STREET 2:		150 NORTH MERAMEC
    		CITY:			CLAYTON
    		STATE:			MO
    		ZIP:			63105

    	FORMER COMPANY:
    		FORMER CONFORMED NAME:	ENTERBANK HOLDINGS INC
    		DATE OF NAME CHANGE:	19961024
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>DEF 14A
    <SEQUENCE>1
    <FILENAME>efsc2020def14a.htm
    <DESCRIPTION>DEF 14A
    <TEXT>
    Document 1 - file: efsc2020def14a.htm

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>2
    <FILENAME>nisignaturea032a.jpg
    <DESCRIPTION>SIGNATURE
    <TEXT>
    Document 2 - file: nisignaturea032a.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>proxycardfinal_pagex11a.jpg
    <DESCRIPTION>PROXYCARDPAGE1
    <TEXT>
    Document 3 - file: proxycardfinal_pagex11a.jpg

    </DOCUMENT>
    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>proxycardfinal_pagex21a.jpg
    <DESCRIPTION>PROXYCARDPAGE2
    <TEXT>
    Document 4 - file: proxycardfinal_pagex21a.jpg

    </DOCUMENT>
    </SEC-DOCUMENT>