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  <xs:element id="efsc_DesMoinesMember" abstract="true" name="DesMoinesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_CommercialAndIndustrialPortfolioSegmentMember" abstract="true" name="CommercialAndIndustrialPortfolioSegmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_ConsumerAndOtherPortfolioSegmentMember" abstract="true" name="ConsumerAndOtherPortfolioSegmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_CashFlowHedge1Member" abstract="true" name="CashFlowHedge1Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_CommercialRealEstateOwnerOccupiedFinancingReceivableMember" abstract="true" name="CommercialRealEstateOwnerOccupiedFinancingReceivableMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_CommercialRealEstateOwnerOccupiedPortfolioSegmentMember" abstract="true" name="CommercialRealEstateOwnerOccupiedPortfolioSegmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_FinancialAsset30to89DaysPastDueMember" abstract="true" name="FinancialAsset30to89DaysPastDueMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_CashFlowHedge4Member" abstract="true" name="CashFlowHedge4Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_RepaymentsOfLongTermFederalHomeLoanBankAdvances" abstract="false" name="RepaymentsOfLongTermFederalHomeLoanBankAdvances" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_OtherMiscellaneousIncomeMember" abstract="true" name="OtherMiscellaneousIncomeMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_OutsideServicesMember" abstract="true" name="OutsideServicesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_Sharesissuedinconnectionwithacquisition" abstract="false" name="Sharesissuedinconnectionwithacquisition" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_BankOwnedLifeInsuranceMember" abstract="true" name="BankOwnedLifeInsuranceMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_ScheduleOfCommitmentsTableTextBlock" abstract="false" name="ScheduleOfCommitmentsTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="efsc_OtherRealEstateMember" abstract="true" name="OtherRealEstateMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_CoveredLoansTable" abstract="true" name="CoveredLoansTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="efsc_LoansAndLeasesReceivableNetReportedAmountFairValueDisclosure" abstract="false" name="LoansAndLeasesReceivableNetReportedAmountFairValueDisclosure" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_FinancingReceivablePaycheckProtectionProgramUnearnedFees" abstract="false" name="FinancingReceivablePaycheckProtectionProgramUnearnedFees" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_OtherRealEstateFairValueDisclosure" abstract="false" name="OtherRealEstateFairValueDisclosure" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_Commonsharesissuedinrelationtoacquisition" abstract="false" name="Commonsharesissuedinrelationtoacquisition" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="xbrli:integerItemType"/>
  <xs:element id="efsc_LoansClassifiedByPerformingStatusMember" abstract="true" name="LoansClassifiedByPerformingStatusMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_UnadvancedCommitmentOnImpairedLoanMember" abstract="true" name="UnadvancedCommitmentOnImpairedLoanMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_Accruedinterestreceivableheldtomaturitysecurities" abstract="false" name="Accruedinterestreceivableheldtomaturitysecurities" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_LoansAndLeasesReceivableImpairedLoansCommitmentToLendReserve" abstract="false" name="LoansAndLeasesReceivableImpairedLoansCommitmentToLendReserve" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_CashFlowHedge2Member" abstract="true" name="CashFlowHedge2Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_GainOnStateTaxCreditsNet" abstract="false" name="GainOnStateTaxCreditsNet" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_ScheduleOfCommitmentsTable" abstract="true" name="ScheduleOfCommitmentsTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="efsc_RealEstateLoansPortfolioSegmentMember" abstract="true" name="RealEstateLoansPortfolioSegmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_LoansByMajorCategoryDomain" abstract="true" name="LoansByMajorCategoryDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_TaxcreditactivitynetMember" abstract="true" name="TaxcreditactivitynetMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_NatureOfCommitmentsDomain" abstract="true" name="NatureOfCommitmentsDomain" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_NetAccretionOfLoanDiscountAndIndemnificationAsset" abstract="false" name="NetAccretionOfLoanDiscountAndIndemnificationAsset" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_CustomerAnalysisExpenseMember" abstract="true" name="CustomerAnalysisExpenseMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_ServicingAssetFairValueDisclosure" abstract="false" name="ServicingAssetFairValueDisclosure" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_FirstChoiceBancorpMember" abstract="true" name="FirstChoiceBancorpMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_LoansClassifiedByRiskCategoryMember" abstract="true" name="LoansClassifiedByRiskCategoryMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_AdjustmentsToAdditionalPaidInCapitalRetirementOfTreasuryStock" abstract="false" name="AdjustmentsToAdditionalPaidInCapitalRetirementOfTreasuryStock" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_OtherExpensesMember" abstract="true" name="OtherExpensesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_FixedRateLoanCommitmentMember" abstract="true" name="FixedRateLoanCommitmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_NatureOfCommitmentsAxis" abstract="true" name="NatureOfCommitmentsAxis" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType"/>
  <xs:element id="efsc_AllowanceForCreditLossesQualitativeAdjustment" abstract="false" name="AllowanceForCreditLossesQualitativeAdjustment" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_FinancingReceivablePaycheckProtectionProgram" abstract="false" name="FinancingReceivablePaycheckProtectionProgram" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_AgriculturePortfolioNicheSegmentMember" abstract="true" name="AgriculturePortfolioNicheSegmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_OtherInvestmentsFairValueDisclosure" abstract="false" name="OtherInvestmentsFairValueDisclosure" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_ProceedsfromPaymentsforShortTermFHLBankBorrowingsFinancingActivities" abstract="false" name="ProceedsfromPaymentsforShortTermFHLBankBorrowingsFinancingActivities" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_AdjustmentsToRetainedEarningsAccumulatedDeficitRetirementOfTreasuryStock" abstract="false" name="AdjustmentsToRetainedEarningsAccumulatedDeficitRetirementOfTreasuryStock" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_FDICAndOtherInsuranceMember" abstract="true" name="FDICAndOtherInsuranceMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_ProvisionForLoanLossesNotCoveredUnderFdicLossShare" abstract="false" name="ProvisionForLoanLossesNotCoveredUnderFdicLossShare" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_FinancingReceivableConverted" abstract="false" name="FinancingReceivableConverted" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_MergerRelatedExpenses" abstract="false" name="MergerRelatedExpenses" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_CollateralPledged" abstract="false" name="CollateralPledged" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_OtherBorrowingsFairValueDisclosure" abstract="false" name="OtherBorrowingsFairValueDisclosure" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_BlanketLienMember" abstract="true" name="BlanketLienMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_NoncoveredLoansMember" abstract="true" name="NoncoveredLoansMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_PaymentsToAcquireStateTaxCreditsHeldForSale" abstract="false" name="PaymentsToAcquireStateTaxCreditsHeldForSale" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_StateTaxCreditsHeldForSaleFairValueDisclosure" abstract="false" name="StateTaxCreditsHeldForSaleFairValueDisclosure" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_CashFlowHedge3Member" abstract="true" name="CashFlowHedge3Member" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_FinancingReceivablePaycheckProtectionProgramNetofDeferredFees" abstract="false" name="FinancingReceivablePaycheckProtectionProgramNetofDeferredFees" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_EnterpriseValueLendingPortfolioNicheSegmentMember" abstract="true" name="EnterpriseValueLendingPortfolioNicheSegmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_ContractualAmountsOfOffBalanceSheetFinancialInstruments" abstract="false" name="ContractualAmountsOfOffBalanceSheetFinancialInstruments" nillable="true" xbrli:periodType="instant" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_ImpairedLoansMember" abstract="true" name="ImpairedLoansMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_DebtSecuritiesHeldToMaturityNetOfAllowanceForCreditLosses" abstract="false" name="DebtSecuritiesHeldToMaturityNetOfAllowanceForCreditLosses" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_LoansByMajorCategoryAxis" abstract="true" name="LoansByMajorCategoryAxis" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:dimensionItem" type="xbrli:stringItemType"/>
  <xs:element id="efsc_AmortizationExpenseMember" abstract="true" name="AmortizationExpenseMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_InterestBearingDepositsGreaterThan90Days" abstract="false" name="InterestBearingDepositsGreaterThan90Days" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_CoveredLoansLineItems" abstract="true" name="CoveredLoansLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="efsc_SalesOfOtherRealEstateFinanced" abstract="false" name="SalesOfOtherRealEstateFinanced" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_AmortizationOfServicingAssets" abstract="false" name="AmortizationOfServicingAssets" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_LoanLegalExpenseMember" abstract="true" name="LoanLegalExpenseMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_FixedAssetsMember" abstract="true" name="FixedAssetsMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_ReclassifiedtoHeldtoMaturityMember" abstract="true" name="ReclassifiedtoHeldtoMaturityMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_BranchClosureExpenses" abstract="false" name="BranchClosureExpenses" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_AOCIAccumulatedGainLossHeldToMaturitySecuritiesParentMember" abstract="true" name="AOCIAccumulatedGainLossHeldToMaturitySecuritiesParentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_LoanServicingAssetMember" abstract="true" name="LoanServicingAssetMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_InitialAllowanceOnAcquiredPCDLoans" abstract="false" name="InitialAllowanceOnAcquiredPCDLoans" nillable="true" xbrli:periodType="duration" xbrli:balance="credit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_FinancingReceivableOriginatedMoreThanSixYearsBeforeCurrentFiscalYear" abstract="false" name="FinancingReceivableOriginatedMoreThanSixYearsBeforeCurrentFiscalYear" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_ConstructionAndLandDevelopmentFinancingReceivableMember" abstract="true" name="ConstructionAndLandDevelopmentFinancingReceivableMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_ImpairedFinancingReceivableRecordedInvestmentExcludingGuaranteedBalances" abstract="false" name="ImpairedFinancingReceivableRecordedInvestmentExcludingGuaranteedBalances" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_IncrementalCommonSharesAttributableToAdditionalDilutiveCommonStockEquivalents" abstract="false" name="IncrementalCommonSharesAttributableToAdditionalDilutiveCommonStockEquivalents" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:sharesItemType"/>
  <xs:element id="efsc_CommercialRealEstateInvestorOwnedPortfolioSegmentMember" abstract="true" name="CommercialRealEstateInvestorOwnedPortfolioSegmentMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_DebtInstrumentRemainingTerm" abstract="false" name="DebtInstrumentRemainingTerm" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="efsc_FinancingReceivableYearSixOriginatedFiveYearsBeforeCurrentFiscalYear" abstract="false" name="FinancingReceivableYearSixOriginatedFiveYearsBeforeCurrentFiscalYear" nillable="true" xbrli:periodType="instant" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_ScheduleOfAccountsNotesLoansAndFinancingReceivableExcludingAllowanceForCreditLossesTableTextBlock" abstract="false" name="ScheduleOfAccountsNotesLoansAndFinancingReceivableExcludingAllowanceForCreditLossesTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="efsc_BasisOfAccountingAndConsolidationPolicyPolicyTextBlock" abstract="false" name="BasisOfAccountingAndConsolidationPolicyPolicyTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="efsc_ScheduleOfCommitmentsLineItems" abstract="true" name="ScheduleOfCommitmentsLineItems" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="efsc_CommercialRealEstateInvestorOwnedFinancingReceivableMember" abstract="true" name="CommercialRealEstateInvestorOwnedFinancingReceivableMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_MortgageBackedSecuritiesWeightedAverageLife" abstract="false" name="MortgageBackedSecuritiesWeightedAverageLife" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:durationItemType"/>
  <xs:element id="efsc_SummaryOfActivityInAllowanceForLoanLossesByPortfolioClassAndCategoryBasedOnImpairmentMethodTable" abstract="true" name="SummaryOfActivityInAllowanceForLoanLossesByPortfolioClassAndCategoryBasedOnImpairmentMethodTable" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrldt:hypercubeItem" type="xbrli:stringItemType"/>
  <xs:element id="efsc_ResidentialRealEstateFinancingReceivableMember" abstract="true" name="ResidentialRealEstateFinancingReceivableMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_CardServicesRevenueMember" abstract="true" name="CardServicesRevenueMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_ProceedsFromSaleOfStateTaxCreditsHeldForSale" abstract="false" name="ProceedsFromSaleOfStateTaxCreditsHeldForSale" nillable="true" xbrli:periodType="duration" xbrli:balance="debit" substitutionGroup="xbrli:item" type="xbrli:monetaryItemType"/>
  <xs:element id="efsc_ChangesInAbstract" abstract="true" name="ChangesInAbstract" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="xbrli:stringItemType"/>
  <xs:element id="efsc_ScheduleOfCollateralDependentLoansTableTextBlock" abstract="false" name="ScheduleOfCollateralDependentLoansTableTextBlock" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:textBlockItemType"/>
  <xs:element id="efsc_DepositorySharesMember" abstract="true" name="DepositorySharesMember" nillable="true" xbrli:periodType="duration" substitutionGroup="xbrli:item" type="dtr-types:domainItemType"/>
  <xs:element id="efsc_MaximumPercentageOfShareholdersEquitySecurityHoldingsHeldOfOneIssuer" abstract="false" name="MaximumPercentageOfShareholdersEquitySecurityHoldingsHeldOfOneIssuer" nillable="true" xbrli:periodType="instant" substitutionGroup="xbrli:item" type="dtr-types:percentItemType"/>
</xs:schema>
