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Collaboration Agreements - Takeda (Details) - Takeda Pharmaceutical Company Limited |  | 1 Months Ended | 90 Months Ended
--- | --- | --- | ---
Feb. 26, 2025 | Dec. 31, 2021 contract | Jun. 30, 2025 USD ($)
Takeda Collaboration Agreement |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |
Remaining performance obligation |  |  | $ 0
Collaborative Arrangement, PTV:PGRN and ATV:TREM2 |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |
Number of new contracts | contract |  | 2 |
Notice period for effective termination | 60 days |  |
Collaborative Arrangement, PTV:PGRN and ATV:TREM2 | Option Fee Payment |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |
Total collaboration revenue |  |  | 10,000,000
Collaborative Arrangement, PTV:PGRN and ATV:TREM2 | Milestone Payment |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |
Total collaboration revenue |  |  | 10,000,000
Collaborative Arrangement, PTV:PGRN and ATV:TREM2 | Product |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |
Total collaboration revenue |  |  | $ 0

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