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Segment Information
 6 Months Ended
Jun. 30, 2025
Segment Reporting [Abstract]  
Segment Information Segment Information
The Company has one operating segment with the goal to discover, develop and commercialize therapeutics (“Therapeutics”). There have been no material changes to the Company's segment structure, the basis of segmentation, or the measurement basis for segment profit or loss or segment assets, compared to those disclosed in Note 14, "Segment Information", to the consolidated financial statements in the Company's 2024 Annual Report on Form 10-K.
The following table presents selected financial information with respect to the Company’s single operating segment for the three and six months ended June 30, 2025 and 2024 (in thousands):
Therapeutics Segment
Three Months Ended June 30,Six Months Ended June 30,
2025202420252024
Expenses
External research and development expenses - TV programs, including cost sharing$37,594 $30,247 $84,052 $65,931 
External research and development expenses - small molecule programs, including cost sharing2,787 12,596 11,641 25,717 
Other research and development expenses22,060 14,504 42,706 30,386 
Personnel related research and development expenses
40,255 34,052 80,524 76,381 
Total research and development expenses102,696 91,399 218,923 198,415 
Personnel related general and administrative expenses
20,115 17,105 38,853 36,190 
Other general and administrative expenses
12,152 8,089 22,767 14,240 
Total general and administrative expenses32,267 25,194 61,620 50,430 
Segment operating expenses134,963 116,593 280,543 248,845 
Segment gain from divestiture of small molecule programs— — — 14,537 
Segment loss from operations(134,963)(116,593)(280,543)(234,308)
Segment interest and other income, net10,844 17,567 23,454 33,480 
Segment loss before income taxes$(124,119)$(99,026)$(257,089)$(200,828)
There is no difference between the segment loss before income taxes and total consolidated loss before income taxes for the three and six months ended June 30, 2025 and 2024.