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Collaboration Agreements - Takeda (Details) - Takeda Pharmaceutical Company Limited
1 Months Ended 90 Months Ended
Feb. 26, 2025
Dec. 31, 2021
contract
Jun. 30, 2025
USD ($)
Takeda Collaboration Agreement      
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]      
Remaining performance obligation     $ 0
Collaborative Arrangement, PTV:PGRN and ATV:TREM2      
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]      
Number of new contracts | contract   2  
Notice period for effective termination 60 days    
Collaborative Arrangement, PTV:PGRN and ATV:TREM2 | Option Fee Payment      
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]      
Total collaboration revenue     10,000,000
Collaborative Arrangement, PTV:PGRN and ATV:TREM2 | Milestone Payment      
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]      
Total collaboration revenue     10,000,000
Collaborative Arrangement, PTV:PGRN and ATV:TREM2 | Product      
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]      
Total collaboration revenue     $ 0