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Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2026
Mar. 31, 2025
Operating expenses:    
Research and development $ 103,846 $ 116,227
General and administration 33,511 29,353
Total operating expenses 137,357 145,580
Loss from operations (137,357) (145,580)
Interest and other income, net 8,910 12,610
Net loss (128,447) (132,970)
Other comprehensive income (loss):    
Net unrealized gain (loss) on marketable securities, net of tax (1,364) 17
Comprehensive loss $ (129,811) $ (132,953)
Net loss per share, basic (usd per share) $ (0.69) $ (0.78)
Net loss per share, diluted (usd per share) $ (0.69) $ (0.78)
Weighted average number of shares outstanding, basic (in shares) 186,636,978 171,222,030
Weighted average number of shares outstanding, diluted (in shares) 186,636,978 171,222,030